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Differences in the prevalence of cardiovascular and metabolic diseases coinciding with clinical subtypes of obstructive sleep apnea

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收录情况： ◇ SCIE

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机构： [1]Department of Otolaryngology-Head and Neck Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [2]Department of Otolaryngology-Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. [3]Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China. [4]Department of Otorhinolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.

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It is unclear about the cardiovascular and metabolic diseases (CMD) among Chinese patients with different clinical subtypes of obstructive sleep apnea (OSA).The prevalence of CMD varies among OSA patients of different clinical subtypes.A total of 1483 Chinese patients with OSA were assessed to evaluate the existence of clinical subtypes of OSA using latent class analysis. We compared the differences in demographic characteristics and prevalence of CMD using ANOVA and χ2 tests. Associations between clinical subtypes and disease prevalence were assessed using adjusted logistic regression.We identified prevalent CMD in Chinese patients with the four subtypes of OSA: excessively sleepy (ES), moderately sleepy with disturbed sleep (ModSwDS), moderately sleepy (ModS), and minimally symptomatic (MinS). The ES subtype had a higher body mass index, average Epworth Sleepiness Scale score, Apnea-hypopnea index, and oxyhemoglobin saturation below 90% compared with the other subtypes (p < .05). The MinS subtype had the lowest mean ESS score (p < .05). We found a significant difference in the prevalence of CMD among the four subtypes, with the highest proportion of cases of CMD in the ES subtype. In adjusted models, significant associations with CMD were also found. ES, ModSwDS, ModS, and MinS subtypes are very high-risk, high-risk, medium-risk, and low-risk in prevalent CMD.This study identified four clinical subtypes of OSA in Chinese patients. Each clinical subtype corresponds with a different level of prevalence of CMD; this finding is helpful for the more precise treatment of patients with different clinical manifestations.© 2022 The Authors. Clinical Cardiology published by Wiley Periodicals LLC.

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出版当年[2022]版：

大类 | 3 区医学

小类 | 3 区心脏和心血管系统

最新[2023]版：

大类 | 3 区医学

小类 | 4 区心脏和心血管系统

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出版当年[2021]版：

Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

最新[2023]版：

Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子： 2.4 最新[2023版] 2.7 最新五年平均 3.287 出版当年[2021版] 3.048 出版当年五年平均 2.882 出版前一年[2020版] 2.7 出版后一年[2022版]

第一作者：

第一作者机构： [1]Department of Otolaryngology-Head and Neck Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [2]Department of Otolaryngology-Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

通讯作者：

通讯机构： [1]Department of Otolaryngology-Head and Neck Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [2]Department of Otolaryngology-Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. [4]Department of Otorhinolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China. [*1]Department of Otolaryngology‐Head and Neck Surgery,Capital Institute of Pediatrics, 2 Yabao Road,Beijing 100045, China. [*2]Department ofOtolaryngology‐Head and Neck Surgery,Xuanwu Hospital, Capital Medical University,45 Changchun St, Xicheng District,Beijing 100053, China

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