机构：[1]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China神经科系统神经外科功能神经外科首都医科大学宣武医院[2]Tianjin Huanhu Hospital, Tianjin, China[3]Functional Neurosurgery Department, Beijing Children's Hospital, Capital Medical University, Beijing, China首都医科大学附属北京儿童医院
This study aimed to differentiate temporal plus epilepsy (TPE) from temporal lobe epilepsy (TLE) using extraction of radiomics features from three-dimensional magnetization-prepared rapid acquisition gradient echo (3D-MPRAGE) imaging data.Data from patients with TLE or TPE who underwent epilepsy surgery between January 2019 and January 2021 were retrospectively analyzed. Thirty-three regions of interest in the affected hemisphere of each patient were defined on 3D-MPRAGE images. A total of 3531 image features were extracted from each patient. Four feature selection methods and 10 machine learning algorithms were used to build 40 differentiation models. Model performance was evaluated using receiver operating characteristic analysis.Eighty-two patients were included for analysis, 47 with TLE and 35 with TPE. The model combining logistic regression and the relief selection method had the best performance (area under the receiver operating characteristic curve, 0.779; accuracy, 0.875; sensitivity, 0.800; specificity, 0.929; positive predictive value, 0.889; negative predictive value, 0.867).Radiomics analysis can differentiate TPE from TLE. The logistic regression classifier trained with radiomics features extracted from 3D-MPRAGE images had the highest accuracy and best performance.This article is protected by copyright. All rights reserved.
基金：
‘Beijing Hospitals Authority’
Ascent Plan, Grant/Award Number:
DFL20190801; Capital Health Research
and Development of Special Project,
Grant/Award Number: 2020-1-2013;
National Natural Science Foundation of
China General Program, Grant/Award
Number: 62171300
第一作者机构：[1]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China[2]Tianjin Huanhu Hospital, Tianjin, China
通讯作者：
通讯机构：[3]Functional Neurosurgery Department, Beijing Children's Hospital, Capital Medical University, Beijing, China[*1]Functional Neurosurgery Department, Beijing Children's Hospital, Capital Medical University, No. 56, Nanlishi Load, Xicheng District, Beijing 100045, China.
推荐引用方式(GB/T 7714)：
Yin Fangzhao,Yan Xiaoming,Gao Runshi,et al.Radiomics features from 3D-MPRAGE imaging can differentiate temporal-plus epilepsy from temporal lobe epilepsy[J].EPILEPTIC DISORDERS.2023,25(5):681-689.doi:10.1002/epd2.20092.
APA：
Yin Fangzhao,Yan Xiaoming,Gao Runshi,Ren Zhiwei,Yu Tao...&Zhang Guojun.(2023).Radiomics features from 3D-MPRAGE imaging can differentiate temporal-plus epilepsy from temporal lobe epilepsy.EPILEPTIC DISORDERS,25,(5)
MLA：
Yin Fangzhao,et al."Radiomics features from 3D-MPRAGE imaging can differentiate temporal-plus epilepsy from temporal lobe epilepsy".EPILEPTIC DISORDERS 25..5(2023):681-689
