机构：[1]Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, China.外科系统骨科首都医科大学宣武医院[2]National Clinical Research Center for Geriatric Diseases, Beihang University, Beijing, China.
A retrospective radiologic study.To identify age-associated changes in T1 slope (T1S) and C7 slope (C7S), as well as the difference between T1S and C7S (△, which was defined as T1S minus C7S) and to explore the cervical morphology that C7S can be the most accurate alternative for the invisible T1S.625 asymptomatic Chinese volunteers received cervical lateral radiographs from August 2021 to May 2022. Occipito-C2 angle (O-C2), C2-7 angle (C2-7), cranial arch, caudal arch, C7S, and T1S were examined. Thereafter, the △ was established. The correlations among T1S, C7S, △ and other cervical sagittal parameters, and between age and other cervical sagittal parameters were evaluated with the Pearson correlation coefficient analysis. Then, analysis of variance (ANOVA) was conducted to compare variations in cervical sagittal parameters among volunteers aged 40 to 59 years, 60 to 64 years, 65 to 69 years, 70 to 74 years, and ≥75 years of age, and among volunteers with 1 lordotic morphology, 2 lordotic morphology, straight morphology, kyphotic morphology, 1 sigmoid morphology, and 2 sigmoid morphology. Linear regression modeling of the correlation between C7S and T1S in various cervical alignment patterns was then established.△ had the strongest correlation with caudal arch (r = .646), and weakest correlation with cranial arch (r = -.082). Age was significantly correlated with T1S (r = .250), C7S (r = .244), and △ (r = .112). Among them, △ was stable until 74 years after which it showed an elevation from 3.3° in the group 70-74 years to 4.1° in the group over 75 years. Moreover, there was marked variation between T1S and C7S at 1 lordotic, 2 lordotic, straight and 2 sigmoid alignment patterns, but no difference was seen between T1S and C7S at kyphotic and 1 sigmoid alignment patterns.There was a progressive increase in T1S, C7S, and △ with age. Linear regression equations for accurate prediction of T1S were developed based on the C7S in 1 lordotic, 2 lordotic, straight and 2 sigmoid alignment patterns. C7S may be a reliable proxy for T1S in kyphotic and 1 sigmoid alignment patterns.
基金：
The author(s) disclosed receipt of the following financial support for
the research, authorship, and/or publication of this article: This studywas supported by the National Key Research and Development
Program of China (No.2020YFC2004900), National Natural Science
Foundation of China (H0608), Natural Science Foundation of China
(No.81672201, 81871794) and Beijing Hospitals Authorit’Ascent
Plan (No.DFL20190802).
第一作者机构：[1]Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, China.[2]National Clinical Research Center for Geriatric Diseases, Beihang University, Beijing, China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, China.[2]National Clinical Research Center for Geriatric Diseases, Beihang University, Beijing, China.[*1]Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Changchun Rd. 45, Beijing 100053, China.[*2]Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Changchun Rd. 45, Beijing 100053, China
推荐引用方式(GB/T 7714)：
Wang Zheng,Hu Xinli,Wang Wei,et al.Can C7 Slope Accurately Substitute for an Invisible T1 Slope According to Age and Cervical Morphology in Cervical Lateral Radiographs?[J].GLOBAL SPINE JOURNAL.2023,doi:10.1177/21925682231192842.
APA：
Wang Zheng,Hu Xinli,Wang Wei,Cui Peng,Zhu Weiguo...&Lu Shibao.(2023).Can C7 Slope Accurately Substitute for an Invisible T1 Slope According to Age and Cervical Morphology in Cervical Lateral Radiographs?.GLOBAL SPINE JOURNAL,,
MLA：
Wang Zheng,et al."Can C7 Slope Accurately Substitute for an Invisible T1 Slope According to Age and Cervical Morphology in Cervical Lateral Radiographs?".GLOBAL SPINE JOURNAL .(2023)
