资源类型：
期刊
WOS体系：
Article
Pubmed体系：
Journal Article
收录情况：
◇ SCIE
文章类型：
论著
机构：
[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Changchun Street 45, Beijing 100053, China
神经科系统
神经内科
首都医科大学宣武医院
ISSN：
1590-1874
关键词：
Behavioral variant of frontotemporal dementia
Mild behavioral impairment checklist
Neuropsychiatric inventory questionnaire
Frontal behavioral inventory
Neuropsychiatric symptoms
摘要：
The mild behavioral impairment checklist (MBI-C) designed to capture neuropsychiatric symptoms in the whole spectrum of elder with or without dementia, have been verified in mild behavioral impairment, mild cognitive impairment and Alzheimer's Disease, but never used in the behavioral variant of frontotemporal dementia (bvFTD).Fifty-two patients with bvFTD (mild, n = 30; moderate-severe, n = 22) and 82 community-dwelling elderly individuals (HCs) were enrolled. All subjects were assessed with a full neuropsychological scale including the MBI-C, Neuropsychiatric Inventory Questionnaire (NPI-Q), and Frontal Behavioral Inventory (FBI). Receiver operating characteristic curves were drawn to analyze the sensitivity and specificity of the MBI-C, NPI-Q, and FBI, and cutoff points were determined using the Youden index.The MBI-C and domain scores in all patients with bvFTD were significantly higher than those in HCs. The most common symptoms of bvFTD were apathy (82.7%) and impulse dyscontrol (80.8%). The MBI-C score was positively correlated with the NPI-Q, FBI, and Activities of Daily Living. For differentiating patients with both bvFTD and mild bvFTD from HCs, the optimal MBI-C cutoff point was 5.5 with a sensitivity of 100% and specificity of 82%, and its sensitivity was higher than that of the NPI-Q and FBI.The MBI-C is a sensitive tool for screening behavioral and psychological symptoms in patients with bvFTD, even in the early stages of the disease.© 2023. The Author(s).
基金：
Beijing Municipal Natural
Science Foundation under Grant 7202060; the National Natural Science Foundation of China under Grant 81971011 and 82271464.
被引次数：
1
WOS：
WOS:001062736300002
PubmedID：
37668827
中科院(CAS)分区：
出版当年[2023]版：
大类
|
4 区
医学
小类
|
4 区
临床神经病学
4 区
神经科学
最新[2023]版：
大类
|
4 区
医学
小类
|
4 区
临床神经病学
4 区
神经科学
JCR分区：
出版当年[2022]版：
Q2
CLINICAL NEUROLOGY
Q3
NEUROSCIENCES
最新[2023]版：
Q2
CLINICAL NEUROLOGY
Q3
NEUROSCIENCES
影响因子：
2.7
最新[2023版]
2.7
最新五年平均
3.3
出版当年[2022版]
3.2
出版当年五年平均
3.83
出版前一年[2021版]
2.7
出版后一年[2023版]
第一作者：
Cui Yue
第一作者机构：
[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Changchun Street 45, Beijing 100053, China
通讯作者：
Wu Liyong
推荐引用方式(GB/T 7714)：
Cui Yue,Liu Li,Chu Min,et al.Application of the mild behavioral impairment checklist in Chinese patients with the behavioral variant of frontotemporal dementia[J].NEUROLOGICAL SCIENCES.2024,45(2):557-564.doi:10.1007/s10072-023-07049-4.
APA：
Cui Yue,Liu Li,Chu Min,Xie Kexin,Chen Zhongyun...&Wu Liyong.(2024).Application of the mild behavioral impairment checklist in Chinese patients with the behavioral variant of frontotemporal dementia.NEUROLOGICAL SCIENCES,45,(2)
MLA：
Cui Yue,et al."Application of the mild behavioral impairment checklist in Chinese patients with the behavioral variant of frontotemporal dementia".NEUROLOGICAL SCIENCES 45..2(2024):557-564
