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Reference intervals of biochemical analytes in healthy adults from northern China: A population-based cross-sectional study

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收录情况： ◇ SCIE

作者：

机构： [1]Trauma Emergency Center, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China. [2]Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, People's Republic of China. [3]Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, People's Republic of China. [4]NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, People's Republic of China. [5]Hebei Orthopedic Clinical Research Center, Shijiazhuang, Hebei, People's Republic of China. [6]Department of Pharmacy, Cangzhou People's Hospital, Cangzhou, Hebei, People's Republic of China. [7]Department of Neurology, Hebei Hospital, Xuanwu Hospital of Capital Medical University, Shijiazhuang, Hebei, China.

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关键词： age biochemical China reference intervals sex

摘要：

Reference intervals (RIs) of laboratory testing play a fundamental role in medical activities. RIs vary greatly for populations in different areas This study aimed to evaluate the age- and sex-specific reference intervals for a healthy population in a typical city of northern China. A cross-sectional study was performed in 4 tertiary care centers of Shijiazhuang of China, biochemical analytes were analyzed using a Beckman Coulter AU5800 (Beckman Coulter Inc., Brea, CA). A total of 42,979 healthy individuals were involved in this study. Grouped by age- and sex-specific, reference intervals of all the measures have been established. We found that different age groups of males and females have significant differences (all P < .001) in levels of various biochemical analytes. We provided a comprehensive age- and sex-specific RIs for biochemical analytes, which showed dynamic changes with both age and sex. For the local population, the reference intervals established here can be adopted in other clinical laboratories after appropriate validation.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

语种：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2022]版：

大类 | 4 区医学

小类 | 4 区医学：内科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区医学：内科

JCR分区：

出版当年[2021]版：

Q3 MEDICINE, GENERAL & INTERNAL

最新[2023]版：

Q2 MEDICINE, GENERAL & INTERNAL

影响因子： 1.4 最新[2023版] 1.6 最新五年平均 1.817 出版当年[2021版] 2.227 出版当年五年平均 1.889 出版前一年[2020版] 1.6 出版后一年[2022版]

第一作者：

第一作者机构： [1]Trauma Emergency Center, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China. [2]Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, People's Republic of China. [3]Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, People's Republic of China. [4]NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, People's Republic of China. [5]Hebei Orthopedic Clinical Research Center, Shijiazhuang, Hebei, People's Republic of China.

通讯作者：

通讯机构： [1]Trauma Emergency Center, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China. [2]Orthopaedic Research Institute of Hebei Province, Shijiazhuang, Hebei, People's Republic of China. [3]Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, People's Republic of China. [4]NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, People's Republic of China. [5]Hebei Orthopedic Clinical Research Center, Shijiazhuang, Hebei, People's Republic of China.

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Reference intervals of biochemical analytes in healthy adults from northern China: A population-based cross-sectional study

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