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HALL: a comprehensive database for human aging and longevity studies

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收录情况： ◇ SCIE

作者：
Li Hao[1,2] * ; Wu Song[3,4,2] * ; Li Jiaming[1,2] * ; Xiong Zhuang[5] * ; Yang Kuan[1,2,6] * ; Ye Weidong[7,8] * ; Ren Jie[1,2,6,9] * ; Wang Qiaoran[1,2] ; Xiong Muzhao[1,2] ; Zheng Zikai[1,2] ; Zhang Shuo[1,2] ; Han Zichu[1,2] ; Yang Peng[1,2] ; Jiang Beier[7] ; Ping Jiale[1,2] ; Zuo Yuesheng[1,2] ; Lu Xiaoyong[1,2] ; Zhai Qiaocheng[7] ; Yan Haoteng[10,11] ; Wang Si[10,11,12] ; Ma Shuai[13,2,9,12] ; Zhang Bing[1] ; Ye Jinlin[7] ; Qu Jing[14,2,15,9,12] ; Yang Yun-Gui[1,2,6] ; Zhang Feng[8] ; Liu Guang-Hui[13,2,15,9,10,11,12] ; Bao Yiming[3,4,2] ; Zhang Weiqi[1,2,6,9,12] ;
机构： [1]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [2]University of Chinese Academy of Sciences, Beijing 100049, China. [3]CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [4]National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [5]Interdisciplinary Institute for Medical Engineering, Fuzhou University, Fuzhou 350002, China. [6]Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China. [7]Department of Vascular Surgery, Quzhou Affiliated Hospital of Wenzhou Medical University, Beijing 100101, China. [8]The Joint Innovation Center for Engineering in Medicine, Quzhou Affiliated Hospital of Wenzhou Medical University, 324000, China. [9]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. [10]Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China. [11]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. [12]Aging Biomarker Consortium, Beijing 100101, China. [13]State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [14]State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [15]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
出处：
DOI： 10.1093/nar/gkad880
ISSN：

摘要：
Diverse individuals age at different rates and display variable susceptibilities to tissue aging, functional decline and aging-related diseases. Centenarians, exemplifying extreme longevity, serve as models for healthy aging. The field of human aging and longevity research is rapidly advancing, garnering significant attention and accumulating substantial data in recent years. Omics technologies, encompassing phenomics, genomics, transcriptomics, proteomics, metabolomics and microbiomics, have provided multidimensional insights and revolutionized cohort-based investigations into human aging and longevity. Accumulated data, covering diverse cells, tissues and cohorts across the lifespan necessitates the establishment of an open and integrated database. Addressing this, we established the Human Aging and Longevity Landscape (HALL), a comprehensive multi-omics repository encompassing a diverse spectrum of human cohorts, spanning from young adults to centenarians. The core objective of HALL is to foster healthy aging by offering an extensive repository of information on biomarkers that gauge the trajectory of human aging. Moreover, the database facilitates the development of diagnostic tools for aging-related conditions and empowers targeted interventions to enhance longevity. HALL is publicly available at https://ngdc.cncb.ac.cn/hall/index.© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

基金：
National Key Research and Development Program of China [2022YF A1103700, 2020YF A0804000, 2020YF A0112200, 2021YFF1201000, 2022YFA1103802, STI2030-Major Projects-2021ZD0202400]; Strategic Priority Research Pro- gram of the Chinese Academy of Sciences [XDB38030200]; Quzhou Technology Projects [2022K46]; National Natu- ral Science Foundation of China [32121001, 81921006, 82125011, 92149301, 92168201, 91949209, 92049304, 92049116, 82192863, 82122024, 82071588, 32000500, 82271600]; Strategic Priority Research Program of the Chi- nese Academy of Sciences [XDA16000000]; CAS Project for Young Scientists in Basic Research [Y SBR -076, Y SBR - 012]; Program of the Beijing Natural Science Foundation [Z190019]; Informatization Plan of Chinese Academy of Sciences [C AS-WX2021SF-0301, C AS-WX2022SDC-XK14, CAS-WX2021SF-0101]; New Cornerstone Science Foun- dation through the XPLORER PRIZE [2021-1045]; Youth Innovation Promotion Association of C AS [E1C AZW0401, 2022083]; Excellent Young Talents Program of Capital Medical University [12300927]; Project for Technology Development of Beijing-affiliated Medical Research Institutes [11000023T000002036310]; Young Elite Scientists Sponsor- ship Program by CAST [YESS20210002]; Excellent Young Talents Training Program for the Construction of Beijing Municipal University Teacher Team [BPHR202203105]. Funding for open access charge: National Key Research and Development Program of China [2022YFA1103700].
语种：
外文
被引次数：
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PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 2 区 生物学
小类 | 2 区 生化与分子生物学
最新[2025]版：
大类 | 2 区 生物学
小类 | 2 区 生化与分子生物学
JCR分区：
出版当年[2021]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2024]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子： 最新[2024版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者：
第一作者机构： [1]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [2]University of Chinese Academy of Sciences, Beijing 100049, China.
共同第一作者：
通讯作者：
通讯机构： [1]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [2]University of Chinese Academy of Sciences, Beijing 100049, China. [3]CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [4]National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China. [6]Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China. [9]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. [10]Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China. [11]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. [12]Aging Biomarker Consortium, Beijing 100101, China. [13]State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [15]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
推荐引用方式(GB/T 7714)：
Li Hao,Wu Song,Li Jiaming,et al.HALL: a comprehensive database for human aging and longevity studies[J].NUCLEIC ACIDS RESEARCH.2023,52(D1):D909-D918.doi:10.1093/nar/gkad880.
APA：
Li Hao,Wu Song,Li Jiaming,Xiong Zhuang,Yang Kuan...&Zhang Weiqi.(2023).HALL: a comprehensive database for human aging and longevity studies.NUCLEIC ACIDS RESEARCH,52,(D1)
MLA：
Li Hao,et al."HALL: a comprehensive database for human aging and longevity studies".NUCLEIC ACIDS RESEARCH 52..D1(2023):D909-D918

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