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Consensus on pediatric epilepsy surgery for young children: an investigation by the China Association Against Epilepsy task force on epilepsy surgery

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机构: [1]Peking Univ First Hosp, Pediat Epilepsy Ctr, Beijing 100000, Peoples R China [2]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100000, Peoples R China [3]Tsinghua Univ, Dept Epilepsy Ctr, Yuquan Hosp, Beijing 100000, Peoples R China [4]Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing 100000, Peoples R China [5]Capital Med Univ, Sanbo Brain Hosp, Dept Neurosurg, Beijing 100000, Peoples R China [6]Capital Med Univ, Xuanwu Hosp, Dept Funct Neurosurg, Beijing 100000, Peoples R China [7]Peking Univ First Hosp, Dept Pediat, Beijing 100000, Peoples R China [8]Capital Med Univ, Beijing Childrens Hosp, Dept Neurol, Beijing 100000, Peoples R China [9]Fudan Univ, Dept Neurosurg, Childrens Hosp, Shanghai 200000, Peoples R China [10]Capital Med Univ, Beijing Childrens Hosp, Dept Funct Neurosurg, Beijing 100000, Peoples R China [11]Peking Univ First Hosp, Dept Neurol, Beijing 100000, Peoples R China
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关键词: Epilepsy surgery Young children Consensus

摘要:
Researchers have widely acknowledged the therapeutic value of epilepsy surgery for drug-resistant epilepsy. Nonetheless, there is a substantial gap in the surgical treatment for appropriate candidates owing to several factors, particularly in the population of young children. To standardize the protocols of preoperative evaluation and surgery of young children for epilepsy surgery, the China Association Against Epilepsy has appointed an expert task force to standardize the protocols of preoperative evaluation and surgery in pediatric epilepsy patients. It adopted the modified Delphi method and performed two rounds of surveys through an anonymous inquiry among 75 experts from four subgroups including pediatric neurologists, epileptologists, pediatric epilepsy surgeons, and functional neurosurgeons. The survey contents contained: (1) the participants, comprising children aged <= 6 years; (2) adopted DRE definition proposed by the International League Against Epilepsy in 2010; and (3) investigated epilepsy surgery, principally referring to curative epilepsy surgeries. The neuromodulation therapies were excluded because of the differences in treatment mechanisms from the above-mentioned surgeries. According to the Delphi process, a consensus was achieved for most aspects by incorporating two rounds of surveys including preoperative assessment, surgical strategies and techniques, and perioperative and long-term postoperative management, despite controversial opinions on certain items. We hope the results of this consensus will improve the level of surgical treatment and management of intractable epilepsy in young children.

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大类 | 4 区 医学
小类 | 4 区 临床神经病学
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Q4 CLINICAL NEUROLOGY

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第一作者机构: [1]Peking Univ First Hosp, Pediat Epilepsy Ctr, Beijing 100000, Peoples R China
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