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Topology Optimization Driven Bone-Remodeling Simulation for Lumbar Interbody Fusion

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收录情况： ◇ SCIE

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机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Neurospine center, China International Neuroscience Institute, Beijing, China, 100530. [2]State Key Laboratory of Structural Analysis for Industrial Equipment, Department of Engineering Mechanics, International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, 116023, P.R. China [3]Ningbo Institute of Dalian University of Technology, No.26 Yucai Road, Jiangbei District, Ningbo, China, 315016.

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关键词： Bone remodeling Stress shielding Lumbar interbody fusion (LIF) Inverse problem Topology optimization

摘要：

This study proposes a numerical approach for simulating bone remodeling in lumbar interbody fusion (LIF). It employs a topology optimization method to drive the remodeling process and uses a pixel function to describe the structural topology and bone density distribution. Unlike traditional approaches based on strain energy density or compliance, this study adopts von Mises stress to guide the remodeling of LIF. A novel pixel interpolation scheme associated with stress criteria is applied to the physical properties of the bone, directly addressing the stress shielding effect caused by the implanted cage, which significantly influences the bone remodeling outcome in LIF. Additionally, a boundary inverse approach is utilized to reconstruct a simplified analysis model. To reduce computational cost while maintaining high structural resolution and accuracy, the Scaled Boundary Finite Element Method (SBFEM) is introduced. The proposed numerical approach successfully generates results that closely resemble human lumbar interbody fusion.Copyright © 2024 by ASME.

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出版当年[2023]版：

大类 | 4 区医学

小类 | 3 区生物物理 4 区工程：生物医学

最新[2023]版：

大类 | 4 区医学

小类 | 3 区生物物理 4 区工程：生物医学

JCR分区：

出版当年[2022]版：

Q4 BIOPHYSICS Q4 ENGINEERING, BIOMEDICAL

最新[2023]版：

Q3 ENGINEERING, BIOMEDICAL Q4 BIOPHYSICS

影响因子： 1.7 最新[2023版] 1.9 最新五年平均 1.7 出版当年[2022版] 2.1 出版当年五年平均 1.899 出版前一年[2021版] 1.7 出版后一年[2023版]

第一作者：

第一作者机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Neurospine center, China International Neuroscience Institute, Beijing, China, 100530.

通讯作者：

通讯机构： [2]State Key Laboratory of Structural Analysis for Industrial Equipment, Department of Engineering Mechanics, International Research Center for Computational Mechanics, Dalian University of Technology, Dalian, 116023, P.R. China [3]Ningbo Institute of Dalian University of Technology, No.26 Yucai Road, Jiangbei District, Ningbo, China, 315016.

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