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Immunosenescence Inventory-a multi-omics database for immune aging research

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收录情况： ◇ SCIE

作者：
Li Hao[1,2,3] * ; Zhao Wei[2,3,4] * ; Yang Fei[2,4] * ; Qiao Qin[1,2] * ; Ma Shuai[3,5,6,7] * ; Yang Kuan[1,3,8] * ; Song Shuhui[2,3,4] * ; Wang Si[7,9,10,11] ; Qu Jing[3,5,6,7,12,13] ; Liu Guang-Hui[3,5,6,7,9,10,13] ; Bao Yiming[2,3,4] ; Zhang Weiqi[1,2,3,6,7,8] ;
机构： [1]China National Center for Bioinformation, Beijing 100101, China. [2]Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. [3]University of Chinese Academy of Sciences, Beijing 100049, China. [4]National Genomics Data Center, China National Center for Bioinformation, Beijing 100101, China. [5]Key Laboratory of Organ Regeneration and Reconstruction, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [6]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. [7]Aging Biomarker Consortium, Beijing 100101, China. [8]Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China. [9]Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China. [10]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. [11]Chongqing Renji Hospital, University of Chinese Academy of Sciences, Chongqing 400062, China. [12]State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [13]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
出处：
DOI： 10.1093/nar/gkae1102
ISSN：

摘要：
The immune system is intricately interconnected with all other bodily systems. As individuals age, the immune system undergoes changes known as immunosenescence, increasing susceptibility to disease, and contributing significantly to the morbidity and mortality observed in older populations. Immunosenescence drives systemic aging and therefore represents a key therapeutic target to extend healthy aging. In recent years, the extensive application of omics technologies has broadened our understanding of aging and immunity, necessitating a comprehensive database to encapsulate these advancements and deepen our insights into immune aging in the era of artificial intelligence. The Immunosenescence Inventory is a pioneering database designed to provide a multidimensional and integrative view of the aging immune system. By leveraging cutting-edge omics technologies and analytical tools, Immunosenescence Inventory offers a comprehensive resource for researchers to explore the intricate relationship between immunosenescence and age-related health outcomes. Furthermore, the database, which aids in the creation of diagnostic tools for immune aging conditions, is now publicly available at https://ngdc.cncb.ac.cn/iaa/home.© The Author(s) 2024. Published by Oxford University Press on behalf of Nucleic Acids Research.

基金：
The National Natural Science Foundation of China [32121001, 82125011, 81921006, 92149301, 92168201,82122024, 82361148131]; the National Key Research and Development Program of China [2022YFA1103700,2020YFA0804000, 2020YFA0112200, the STI2030- Major Projects-2021ZD0202400, 2021YFF1201000,2021YFA1101000]; the National Natural Science Foundation of China [82330044, 32341001, 92049304, 92049116,82192863, 82071588, 82361148130, 82322025, 82271600];CAS Project for Young Scientists in Basic Research [YSBR076, YSBR-012]; the Program of the Beijing Natural Science Foundation [Z230011, Z240018, JQ24044]; the Informatization Plan of Chinese Academy of Sciences [CASWX2022SDC-XK14]; New Cornerstone Science Foundation through the XPLORER PRIZE [2021-1045]; Youth Innovation Promotion Association of CAS [2022083]; Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research Institutes [JYY2023-13]; CAS Youth Interdisciplinary Team, Excellent Young Talents Program of Capital Medical University [12300927]; the Project for Technology Development of Beijing-affiliated Medical Research Institutes [11000023T000002036310]; Excellent Young Talents Training Program for the Construction of Beijing Municipal University Teacher Team [BPHR202203105]; Young Elite Scientists Sponsorship Program by CAST [2021QNRC001];Initiative Scientific Research Program, Institute of Zoology,Chinese Academy of Sciences [2023IOZ0102]; the National Key Research and Development Program of China [2021YFF0703700, 2021YFF0703701]; Genomics Data Center Operation and Maintenance of Chinese Academy of Sciences [CAS-WX2022SDC-XK05]; the National Natural Science Foundation of China [32300468]; the National Natural Science Foundation of China [92374201].
语种：
外文
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中科院(CAS)分区：
出版当年[2023]版：
大类 | 2 区 生物学
小类 | 2 区 生化与分子生物学
最新[2023]版：
大类 | 2 区 生物学
小类 | 2 区 生化与分子生物学
JCR分区：
出版当年[2022]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2023]版：
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

第一作者：
第一作者机构： [1]China National Center for Bioinformation, Beijing 100101, China. [2]Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. [3]University of Chinese Academy of Sciences, Beijing 100049, China.
共同第一作者：
通讯作者：
通讯机构： [1]China National Center for Bioinformation, Beijing 100101, China. [2]Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. [3]University of Chinese Academy of Sciences, Beijing 100049, China. [4]National Genomics Data Center, China National Center for Bioinformation, Beijing 100101, China. [5]Key Laboratory of Organ Regeneration and Reconstruction, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [6]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. [7]Aging Biomarker Consortium, Beijing 100101, China. [8]Sino-Danish College, University of Chinese Academy of Sciences, Beijing 101408, China. [9]Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China. [10]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. [12]State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. [13]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
推荐引用方式(GB/T 7714)：
Li Hao,Zhao Wei,Yang Fei,et al.Immunosenescence Inventory-a multi-omics database for immune aging research[J].Nucleic Acids Research.2024,doi:10.1093/nar/gkae1102.
APA：
Li Hao,Zhao Wei,Yang Fei,Qiao Qin,Ma Shuai...&Zhang Weiqi.(2024).Immunosenescence Inventory-a multi-omics database for immune aging research.Nucleic Acids Research,,
MLA：
Li Hao,et al."Immunosenescence Inventory-a multi-omics database for immune aging research".Nucleic Acids Research .(2024)

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