Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion directions and fiber geometry, and existing diffusion tractography methods of CNs identification are prone to producing erroneous trajectories and missing true positive connections. To overcome the above challenge, we propose a novel CNs identification framework with anatomy-guided fiber trajectory distribution, which incorporates anatomical shape prior knowledge during the process of CNs tracing to build diffusion tensor vector fields. We introduce higher-order streamline differential equations for continuous flow field representations to directly characterize the fiber trajectory distribution of CNs from the tract-based level. The experimental results on the vivo HCP dataset and the clinical MDM dataset demonstrate that the proposed method reduces false-positive fiber production compared to competing methods and produces reconstructed CNs (i.e. CN II, CN III, CN V, and CN VII/VIII) that are judged to better correspond to the known anatomy.
基金:
National Natural Science Foundation of China [62002327, 61976190, U22A2040]; Natural Science Foundation of Zhejiang Province [LQ23F030017]
语种:
外文
WOS:
第一作者:
第一作者机构:[1]Zhejiang Univ Technol, Coll Informat Engn, Hangzhou, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Xie Lei,Zeng Qingrun,Zhou Huajun,et al.ANATOMY-GUIDED FIBER TRAJECTORY DISTRIBUTION ESTIMATION FOR CRANIAL NERVES TRACTOGRAPHY[J].IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING, ISBI 2024.2024,doi:10.1109/ISBI56570.2024.10635408.
APA:
Xie, Lei,Zeng, Qingrun,Zhou, Huajun,Xie, Guoqiang,Li, Mingchu...&Feng, Yuanjing.(2024).ANATOMY-GUIDED FIBER TRAJECTORY DISTRIBUTION ESTIMATION FOR CRANIAL NERVES TRACTOGRAPHY.IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING, ISBI 2024,,
MLA:
Xie, Lei,et al."ANATOMY-GUIDED FIBER TRAJECTORY DISTRIBUTION ESTIMATION FOR CRANIAL NERVES TRACTOGRAPHY".IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING, ISBI 2024 .(2024)