个人科研网厅 | | 帮助
首都医科大学宣武医院知识库
高级检索
当前位置： 首页 > 详情页

A Novel Surgical Technique for Post-traumatic Syringomyelia Progressing to the Medulla Oblongata: Evidence of Upward Drainage of Central Canal Fluid Within the Spinal Cord

| 认领 | 导出 | |

文献详情

资源类型：
Pubmed体系：
作者：
Yuan Chenghua[1,2,3,4,5] * ; Xiong Zhencheng[6] * ; Lv Houyuan[1,2,3,4,5] * ; Ding Chenyuan[1,2,3,4,5] ; Xia Pingchuan[7] ; Xue Huixin[7] ; Zhan Hui[8] ; Li Mingchu[1,9] ; Du Yueqi[1,2,3,4,5] ; Zhang Can[1,2,3,4,5] ; Liu Zhenlei[1,2,3,4,5] ; Wang Kai[1,2,3,4,5] ; Duan Wanru[1,2,3,4,5] ; Wang Zuowei[1,2,3,4,5] ; Wang Xingwen[1,2,3,4,5] ; Wu Hao[1,2,3,4,5] ; Chen Zan[1,2,3,4,5] ; Jian Fengzeng[1,2,3,4,5] ; Guan Jian[1,2,3,4,5] ;
机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing , China. [2]Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing , China. [3]Research Center of Spine and Spinal Cord, Beijing Institute of Brain Disorders, Capital Medical University, Beijing , China. [4]Lab of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHINA-INI), Beijing , China. [5]National Center for Neurological Disorders, Beijing , China. [6]Department of Orthopaedic Surgery, Trauma Medical Center, West China Hospital, West China Medical School, Sichuan University, Chengdu , Sichuan Province , China. [7]Xuanwu Hospital, Capital Medical University, Beijing , China. [8]The Chinese University of Hong Kong, Hong Kong SAR , China. [9]Department of Neurosurgery, Samii Clinical Neuroanatomy Research &amp [10] Learning Center, Xuanwu Hospital, Capital Medical University, Beijing , China.
出处：
DOI： 10.1227/neu.0000000000003378
ISSN：

摘要：
The exact pathways of fluid outflow within the central canal (CC) of the spinal cord are not completely understood. The best management approach for patients with post-traumatic syringomyelia that progresses to the cranial end of the CC, also known as post-traumatic syringobulbia (PT-syringobulbia), is still a topic of debate. This study aims to introduce a new surgical indication for the foramen magnum and foramen of Magendie dredging (FMMD) procedure in patients with PT-syringobulbia and prospectively assess its surgical outcomes.The study included 15 consecutive patients with symptomatic PT-syringobulbia who underwent the FMMD procedure and 20 patients who underwent traditional arachnolysis. The surgical procedure included decompression of the foramen magnum, removal of all potential intradural factors, and clearance of any possible obstructions at the foramen magnum and the foramen of Magendie. The major presenting symptoms or signs were assessed in terms of symptom improvement, stabilization, or deterioration. Preoperative MRI and postoperative MRI were used to assess syringobulbia resolution. The mean follow-up period was 24 months (range 12-60 months).Twelve patients showed clinical improvement, and 3 were stable. The mean length of the syrinx observed on preoperative MRI was 17.3 spinal levels, and the mean syringobulbia/medulla oblongata index was 69%. The mean syringobulbia/medulla oblongata index observed on postoperative MRI was 29%. The values were significantly lower than the preoperative values ( P < .01). Statistical analysis revealed no significant differences in age, sex, or initial clinical/radiological presentation between the FMMD and arachnolysis groups ( P > .05). However, the FMMD group showed superior outcomes compared with the arachnolysis group, including better clinical improvement, syringomyelia regression, lower complication rates, and reduced revision surgery rates ( P < .01).FMMD emerges as a potentially safe and effective surgical strategy for post-traumatic syringobulbia by restoring physiological fluid outflow through the cranial end of CC in midterm follow-up.Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Congress of Neurological Surgeons.

语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类 | 2 区 医学
小类 | 2 区 临床神经病学 2 区 外科
最新[2025]版：
大类 | 2 区 医学
小类 | 2 区 临床神经病学 2 区 外科
第一作者：
第一作者机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing , China. [2]Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing , China. [3]Research Center of Spine and Spinal Cord, Beijing Institute of Brain Disorders, Capital Medical University, Beijing , China. [4]Lab of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHINA-INI), Beijing , China. [5]National Center for Neurological Disorders, Beijing , China.
共同第一作者：
通讯作者：
通讯机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing , China. [2]Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing , China. [3]Research Center of Spine and Spinal Cord, Beijing Institute of Brain Disorders, Capital Medical University, Beijing , China. [4]Lab of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHINA-INI), Beijing , China. [5]National Center for Neurological Disorders, Beijing , China.
推荐引用方式(GB/T 7714)：
Yuan Chenghua,Xiong Zhencheng,Lv Houyuan,et al.A Novel Surgical Technique for Post-traumatic Syringomyelia Progressing to the Medulla Oblongata: Evidence of Upward Drainage of Central Canal Fluid Within the Spinal Cord[J].Neurosurgery.2025,doi:10.1227/neu.0000000000003378.
APA：
Yuan Chenghua,Xiong Zhencheng,Lv Houyuan,Ding Chenyuan,Xia Pingchuan...&Guan Jian.(2025).A Novel Surgical Technique for Post-traumatic Syringomyelia Progressing to the Medulla Oblongata: Evidence of Upward Drainage of Central Canal Fluid Within the Spinal Cord.Neurosurgery,,
MLA：
Yuan Chenghua,et al."A Novel Surgical Technique for Post-traumatic Syringomyelia Progressing to the Medulla Oblongata: Evidence of Upward Drainage of Central Canal Fluid Within the Spinal Cord".Neurosurgery .(2025)

资源点击量：17069 今日访问量：0 总访问量：916 更新日期：2025-04-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学宣武医院 技术支持：重庆聚合科技有限公司 地址：北京市西城区长椿街45号宣武医院