机构：[1]Department of Neurology, Medical College of Georgia, Augusta University.[2]Department of Neurology, Aarhus University Hospital and Clinical Medicine, Aarhus University, Aarhus, Denmark.[3]Department of Neurology, Xuanwu Hospital, Capitol Medical University, Beijing, China.神经科系统神经内科首都医科大学宣武医院
出处：
摘要：
Chronic remote ischemic conditioning (C-RIC) is the month-long or more intervention of RIC. C-RIC has shown promise in a large randomized clinical trial in intracranial atherosclerotic stenosis (ICAS) to reduce the risk of stroke. C-RIC has the potential to reduce cognitive impairment in cerebral small vessel disease (cSVD). C-RIC is effective in a preclinical model of vascular cognitive impairment and dementia (VCID), the bilateral carotid stenosis model in mice, at reducing cognitive impairment, and white matter damage. C-RIC is safe and shows promise in pilot clinical trials of cSVD. In cohort studies, physical exercise is effective at preventing stroke in ICAS and in slowing the progression of cognitive decline in cSVD. C-RIC shares common mechanisms with physical exercise and is an attractive therapy for cSVD. Dosing and compliance are two issues that need to be resolved before large phase II-III trials in cSVD can be optimized.
语种：
外文
PubmedID：
第一作者：
第一作者机构：[1]Department of Neurology, Medical College of Georgia, Augusta University.
推荐引用方式(GB/T 7714)：
Hess David C,Bruno Askiel,Khan Mohammad B,et al.The Potential of Chronic Remote Ischemic Conditioning in Cerebral Small Vessel Disease[J].Conditioning Medicine.2024,7(1):6-10.
APA：
Hess David C,Bruno Askiel,Khan Mohammad B,Kamat Pradip,Blauenfeldt Rolf Ankerlund...&Ji Xunming.(2024).The Potential of Chronic Remote Ischemic Conditioning in Cerebral Small Vessel Disease.Conditioning Medicine,7,(1)
MLA：
Hess David C,et al."The Potential of Chronic Remote Ischemic Conditioning in Cerebral Small Vessel Disease".Conditioning Medicine 7..1(2024):6-10
