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Ossification of posterior longitudinal ligament of the cervical spine: A review article

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机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing, China [3]Research Center of Spine and Spinal Cord, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China [4]Lab of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHINA-INI), Xuanwu Hospital, Capital Medical University, Beijing, China [5]Department of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China [6]Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
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关键词: Ossification of posterior longitudinal ligament (OPLL) Bone morphogenetic proteins The posterior longitudinal ligament Cervical vertebra review

摘要:
This article reviews the literature on the status of cervical OPLL in recent years, and reviews the etiology, clinical manifestations, imaging features, treatment and prognosis. Evidence was collected through PubMed and Google Scholar databases. After screening, weight removal and irrelevant articles, 57 articles were finally included in the review. Imaging is the only way to confirm the diagnosis, and CT and MRI are used to assess the patient's ossified material and spinal cord compression. Because there are hundreds of surgical approaches to cervical OPLL, each with advantages and disadvantages, clinicians must develop a personalized surgical plan based on the patient's preoperative relevant factors to maximize prognosis. Clinicians should also actively follow up on discharged patients, carefully analyze cases with a poor prognosis, and summarize their experiences.Copyright © 2025. Published by Elsevier España, S.L.U.

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第一作者:
第一作者机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing, China [3]Research Center of Spine and Spinal Cord, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China [4]Lab of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHINA-INI), Xuanwu Hospital, Capital Medical University, Beijing, China
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通讯作者:
通讯机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing, China [3]Research Center of Spine and Spinal Cord, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China [4]Lab of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHINA-INI), Xuanwu Hospital, Capital Medical University, Beijing, China
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