Hearing is one of the most vital sensory functions in human beings and a crucial means of perceiving and acquiring information from the natural environment. The advancement of human society is closely linked to the development of language, with hearing serving as the foundation for verbal communication. As individuals age, the deterioration of the auditory system becomes a significant factor contributing to sensory impairments in the elderly. In addition to hearing loss, the aging of the auditory system is also associated with cognitive decline and psychosocial disorders, which severely impact the quality of life for older adults. Currently, there are no effective treatments or interventions available for addressing the aging of the auditory system. Therefore, identifying biomarkers of the auditory system aging is of great significance. The Aging Biomarker Consortium of China has conducted a comprehensive evaluation of aging biomarkers in the auditory system, focusing on three dimensions: morphological, functional, and humoral biomarkers. This initiative aims to establish a foundation for assessing the degree of aging in the auditory system and to promote the management of auditory health in an aging society, ultimately enhancing the auditory health of the elderly population both in China and globally.
基金：
This work was supported by the Major Program of the National Natural Science Foundation of China (No. 82192863) and the National Natural Science Foundation of China (Nos. 82322019, 82471168).
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类|4 区医学
小类|4 区医学：研究与实验
最新[2025]版：
大类|4 区医学
小类|4 区医学：研究与实验
第一作者：
第一作者机构：[1]Shandong First Med Univ & Shandong Acad Med Sci, Shandong Prov Hosp, Med Sci & Technol Innovat Ctr, Sch Clin & Basic Med Sci, Jinan 250117, Peoples R China
共同第一作者：
通讯作者：
通讯机构：[7]Fudan Univ, ENT Inst, Shanghai 200433, Peoples R China[8]Fudan Univ, Eye & ENT Hosp, Dept Otorhinolaryngol, Shanghai 200433, Peoples R China[12]Sixth Med Ctr Chinese PLA Gen Hosp, Med Sch Chinese PLA, Sr Dept Otolaryngol Head & Neck Surg, Beijing 100853, Peoples R China[13]State Key Lab Hearing & Balance Sci, Beijing 100853, Peoples R China[14]Natl Clin Res Ctr Otolaryngol Dis, Beijing 100853, Peoples R China[28]Fudan Univ, Eye & ENT Hosp, Dept Otorhinolaryngol, State Key Lab Med Neurobiol, Shanghai 200031, Peoples R China[29]Fudan Univ, MOE Frontiers Ctr Brain Sci, MOE Engn Res Ctr Gene Technol, Shanghai 200031, Peoples R China[30]China Natl Ctr Bioinformat, Beijing 100101, Peoples R China[31]Chinese Acad Sci, Beijing Inst Genom, Beijing 100101, Peoples R China[32]Shandong Univ, Qilu Hosp, NHC Key Lab Otorhinolaryngol, Jinan 250012, Peoples R China[33]Shandong Univ, Sch Basic Med Sci, Jinan 250012, Peoples R China[35]Fudan Univ, Otorhinolaryngol Dept Eye, Shanghai 200031, Peoples R China[36]Fudan Univ, ENT Hosp, State Key Lab Med Neurobiol, Shanghai 200031, Peoples R China[37]Fudan Univ, MOE Frontiers Ctr Brain Sci, Shanghai 200031, Peoples R China[40]Shandong Univ, Sch Life Sci, Jinan 250100, Peoples R China[41]Shandong Univ, Key Lab Minist Educ Expt Teratol, Jinan 250100, Peoples R China[46]Southeast Univ, Zhongda Hosp, Adv Inst Life & Hlth, Sch Life Sci & Technol,Dept Otolaryngol Head & Nec, Nanjing 210096, Peoples R China[47]Nantong Univ, Coinnovat Ctr Neuroregenerat, Nantong 226001, Peoples R China[48]Beijing Inst Technol, Inst Engn Med, Sch Med technol, Beijing 100081, Peoples R China
推荐引用方式(GB/T 7714)：
Fu Xiaolong,Wang Si,Wu Yunhao,et al.A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement[J].LIFE MEDICINE.2025,4(1):doi:10.1093/lifemedi/lnaf011.
APA：
Fu, Xiaolong,Wang, Si,Wu, Yunhao,Sun, Yu,Liu, Wenwen...&Chai, Renjie.(2025).A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement.LIFE MEDICINE,4,(1)
MLA：
Fu, Xiaolong,et al."A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement".LIFE MEDICINE 4..1(2025)
