Differentiating Transition Zone Cancers From Benign Prostatic Hyperplasia by Histogram Analysis of Apparent Diffusion Coefficient Maps With Standard and Ultrahigh b-value Diffusion-weighted MR Imaging
机构：[1]Department of Radiology, the Affiliated Changshu Hospital of Soochow University, Changshu No.1 Hospital, Changshu, Jiangsu, China[2]Department of Radiology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China[3]Department of Pathology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China[4]GE Healthcare, Shanghai, China.
Objective To compare the diagnostic performance of standard and ultrahigh b-value Diffusion-weighted Imaging (DWI) using volumetric histogram analysis in differentiating transition zone (TZ) cancer from benign prostatic hyperplasia (BPH). Methods 57 TZ cancer and 61 BPH patients received standard (1000 s/mm(2)) and ultrahigh b-value (2000 s/mm(2)) DWI. The diagnostic ability of ADC histogram parameters derived from two DWI for differentiating TZ cancer from BPH was determined by receiver operating characteristic curve. Results Median, minimum, the 10th, 25th percentile ADC in both ADC(1000) and ADC(2000) and skewness in ADC(2000) had significant differences between TZ cancer and BPH (for all, P < 0.05).The 10th percentile ADC showed highest area under the ROC curve (AUC) in both ADC(1000) and ADC(2000).The 10th percentile ADC of ADC(2000) showed significantly higher AUC than did ADC(1000) (P = 0.0385). Conclusions The 10th percentile ADC obtained from ultrahigh b-value DWI performed better for differentiating TZ cancer from BPH.
基金：
Zhi-hua Lu and Li-biao Ji are
currently receiving a grant (SYSD2017018) from Suzhou industry
technological innovation; Wen-lu Zhao and Jun-kang Shen are currently
receiving a grant (SS201534) from Suzhou Science and Technology
Develop Plan and a grant (XKQ2015009) from The Dominant Clinical
Group of the Second Affiliated Hospital of Soochow University.
第一作者机构：[1]Department of Radiology, the Affiliated Changshu Hospital of Soochow University, Changshu No.1 Hospital, Changshu, Jiangsu, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Radiology, the Affiliated Changshu Hospital of Soochow University, Changshu No.1 Hospital, Changshu, Jiangsu, China[2]Department of Radiology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
推荐引用方式(GB/T 7714)：
Zhi-hua Lu,Li-biao Ji,Wen-lu Zhao,et al.Differentiating Transition Zone Cancers From Benign Prostatic Hyperplasia by Histogram Analysis of Apparent Diffusion Coefficient Maps With Standard and Ultrahigh b-value Diffusion-weighted MR Imaging[J].JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY.2019,43(2):235-241.doi:10.1097/RCT.0000000000000829.
APA：
Zhi-hua Lu,Li-biao Ji,Wen-lu Zhao,Yong-sheng Zhang,Jiang-fen Wu...&Jun-kang Shen.(2019).Differentiating Transition Zone Cancers From Benign Prostatic Hyperplasia by Histogram Analysis of Apparent Diffusion Coefficient Maps With Standard and Ultrahigh b-value Diffusion-weighted MR Imaging.JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY,43,(2)
MLA：
Zhi-hua Lu,et al."Differentiating Transition Zone Cancers From Benign Prostatic Hyperplasia by Histogram Analysis of Apparent Diffusion Coefficient Maps With Standard and Ultrahigh b-value Diffusion-weighted MR Imaging".JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 43..2(2019):235-241
