机构：[1]Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.[2]Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu, China.[3]College of Physical Science and Technology, Sichuan University, Chengdu, China.[4]Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK.[5]Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.[6]Department of Radiology, Second Affiliated Hospital of Soochow University, Suzhou, China
This study aimed to evaluate the imaging quality of head and neck computed tomographic angiography (CTA) in pediatric patients at a lowered radiation dose by combining an iterative model reconstruction (IMR) with low voltage scanning. Eighty-three pediatric patients were randomized into two groups as follows: Group A (n = 42), 100 kV/50 ml contrast media (CM), using filtered back projection (FBP); and Group B (n = 41), 80 kV/30 ml CM, using IMR. The enhanced CT value of the arteries, the image noise, the signal-to-noise ratio (SNR)/contrast-to-noise ratio (CNR), the image quality, the effective radiation dose (ED) and the iodine intake were compared between the two groups. The mean ED and iodine intake of group B were reduced by 69.8% and 40.0%, respectively, compared to those of group A. The mean CT values of the arteries in group B were higher than those in group A (p < 0.01), whereas the image noise of group B was lower than that of group A (p < 0.01). Group B exhibited a better image quality and a higher mean CNR/SNR than that of group A (p < 0.01). Compared to FBP, IMR in head and neck CTA enables a significant reduction in the radiation dose while preserving the diagnostic image quality. Thus, IMR, combined with low tube voltage scanning, provided an excellent solution for improving the image quality of craniocervical vessels in children.
基金：
This study was supported by the Chinese National Natural Science Foundation (Grant No. 81401398), the
program for Changjiang Schloars and Innovative Research Team in University (PCSIRT, Grant No. IRT0935) and
the Suzhou Municipal Science and Technology Guiding Project (Grant No. SYSD2016088).
第一作者机构：[1]Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.[2]Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu, China.
通讯作者：
通讯机构：[6]Department of Radiology, Second Affiliated Hospital of Soochow University, Suzhou, China
推荐引用方式(GB/T 7714)：
Bochao Cheng,Haoyang Xing,Du Lei,et al.Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children[J].SCIENTIFIC REPORTS.2018,8(1):12613.doi:10.1038/s41598-018-30300-4.
APA：
Bochao Cheng,Haoyang Xing,Du Lei,Yingkun Guo,Gang Ning...&Wu Cai.(2018).Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children.SCIENTIFIC REPORTS,8,(1)
MLA：
Bochao Cheng,et al."Impact of iterative model reconstruction combined with dose reduction on the image quality of head and neck CTA in children".SCIENTIFIC REPORTS 8..1(2018):12613
