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Risk factors for and causes and treatment of recurrence of inferior vena cava type of Budd-Chiari syndrome after stenting in China: A retrospective analysis of a large cohort

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机构: [1]Department of Vascular Surgery, the Second Affiliated Hospital of Soochow University, 1055, Sanxiang Rd, Suzhou 215000, Jiangsu, China
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关键词: Budd chiari syndrome Stents Recurrence Risk factors Hypercoagulability

摘要:
To explore the risk factors for recurrence of inferior vena cava (IVC)-type Budd-Chiari syndrome (BCS) after stenting and evaluate the feasibility and primary outcomes of endovascular therapies for recurrent BCS. A retrospective analysis of 219 patients was performed to identify risk factors for recurrence. The images of the recurrent patients during follow-up duration and interventional surgery were also reviewed to find the possible reasons of recurrence. The outcome of endovascular therapies for recurrent BCS was evaluated by Kaplan-Meier analysis. Among the 219 patients, 172 patients with primary IVC-type BCS underwent stenting and 28 patients experienced recurrence. Multivariate analysis identified age, Child-Pugh score, MELD and total bilirubin as independent recurrent indicators. Possible causes of recurrence include thrombosis in the stent, re-obstruction in or above the stent, and stent-related hepatic vein obstruction. Twenty-five patients with recurrent BCS underwent endovascular therapies with a few complications and achieved a high level of short- and mid-term patency. Age, total bilirubin and severity of liver function are the main risk factors for BCS recurrence. These risks might contribute to thrombosis or subsequent fibrous obstruction. Endovascular therapies are effective and safe management options that yield positive outcomes for recurrent BCS. Risk factors for recurrent Budd-Chiari syndrome were identified by multivariate analysis. Causes of recurrent Budd-Chiari syndrome were investigated by assessing radiological images. There is a correlation between risk factors and causes of recurrence. Endovascular therapies for recurrent Budd-Chiari syndrome are effective and safe.

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出版当年[2016]版:
大类 | 2 区 医学
小类 | 2 区 核医学
最新[2025]版:
大类 | 2 区 医学
小类 | 2 区 核医学
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出版当年[2015]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2024]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2024版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

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第一作者机构: [1]Department of Vascular Surgery, the Second Affiliated Hospital of Soochow University, 1055, Sanxiang Rd, Suzhou 215000, Jiangsu, China
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通讯机构: [1]Department of Vascular Surgery, the Second Affiliated Hospital of Soochow University, 1055, Sanxiang Rd, Suzhou 215000, Jiangsu, China
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