Background: Early onset peritonitis (EOP) is not uncommon in peritoneal dialysis patients. We aimed to compare the prognosis of EOP and non-EOP peritoneal dialysis patients. Methods: This study included subjects that underwent PD from January 1, 2004 to July 31, 2013. Patient characteristics were collected. EOP was defined as peritonitis occurring within 6 months after initiation of PD. Patient and technique survival were compared between EOP and non-EOP patients using Cox regression analyses. Results: In total, 189 subjects were included in this study. Patients were divided into EOP (n = 55) and non-EOP groups (n = 134). There was no significant difference in the causative organisms of peritonitis between the two groups. After adjusting for age, diabetes status, serum albumin level and residual renal function, the multivariable Cox regression model revealed that EOP was an independent risk factor for patient mortality (HR 2.03, RI 1.09-3.80, p = 0.026), technique failure (HR 1.69, RI 1.12-2.87, p = 0.015) and total survival (HR 1.73, RI 1.12-2.68, p = 0.013). Conclusions: EOP was identified as an independent risk factor for mortality and technique failure in peritoneal dialysis patients.
基金：
This work was supported by grants from the National Nature Science Foundation
of China (81302584).
第一作者机构：[1]Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou 215000, Jiangsu, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou 215000, Jiangsu, China
推荐引用方式(GB/T 7714)：
Sheng Feng,Yancai Wang,Beifen Qiu,et al.Impact of early-onset peritonitis on mortality and technique survival in peritoneal dialysis patients[J].SPRINGERPLUS.2016,5(1):1676.doi:10.1186/s40064-016-3369-9.
APA：
Sheng Feng,Yancai Wang,Beifen Qiu,Zhi Wang,Linseng Jiang...&Huaying Shen.(2016).Impact of early-onset peritonitis on mortality and technique survival in peritoneal dialysis patients.SPRINGERPLUS,5,(1)
MLA：
Sheng Feng,et al."Impact of early-onset peritonitis on mortality and technique survival in peritoneal dialysis patients".SPRINGERPLUS 5..1(2016):1676
