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Genomic Characterization of Enterobacter cloacae Isolates from China That Coproduce KPC-3 and NDM-1 Carbapenemases

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收录情况: ◇ SCIE

机构: [a]Department of Clinical Laboratory, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China [b]Public Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA [c]Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
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Here, we report two Enterobacter cloacae sequence type 231 isolates coproducing KPC-3 and NDM-1 that have caused lethal infections in a tertiary hospital in China. The bla(NDM-1)-harboring plasmids carry IncA/C-2 and IncR replicons, showing a mosaic plasmid structure, and the bla(NDM-1) is harbored on a novel class I integron-like element. bla(KPC-3) is located on a Tn3-Delta bla(TEM-1)-bla(KPC-3)-Delta Tn1722 element, flanked by two 9-bp direct-repeat sequences and harbored on an IncX6 plasmid.

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出版当年[2015]版:
大类 | 2 区 医学
小类 | 2 区 微生物学 2 区 药学
最新[2023]版:
大类 | 2 区 医学
小类 | 1 区 药学 2 区 微生物学
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出版当年[2014]版:
Q1 PHARMACOLOGY & PHARMACY Q1 MICROBIOLOGY
最新[2023]版:
Q1 PHARMACOLOGY & PHARMACY Q2 MICROBIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [a]Department of Clinical Laboratory, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China [b]Public Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA
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通讯机构: [a]Department of Clinical Laboratory, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China [b]Public Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA
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