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C-Reactive Protein Rethinking its Role in Evaluating the Severity of Hyperlipidemic Acute Pancreatitis

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机构: [1]Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai [2]Department of Gastroenterology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province [3]Department of Gastroenterology, The First People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China.
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关键词: C-reactive protein hypertriglyceridemia lipase pancreatitis severe acute pancreatitis

摘要:
Objectives: The goal of this study is to evaluate the role of C-reactive protein (CRP) in predicting the severity of hyperlipidemic acute pancreatitis (HLAP) compared with non-HLAP (NHLAP). Methods: A total of 1073 episodes of acute pancreatitis between July 2009 and June 2013 were retrospectively studied. The clinical characteristics and laboratory data of HLAP and NHLAP were statistically analyzed on days 1, 2, 3, 4, and 6, especially the CRP level. Results: There was a significant difference in CRP levels between HLAP and NHLAP (P < 0.01) on days 1, 2, 3, 4, and 6. The cutoff value for CRP in HLAP should be greater than NHLAP to obtain an accurate prediction of severity. Higher serum CRP levels in HLAP cases were correlated with higher incidences of diabetes and fatty liver and lower incidences in women, elevated very-low-density lipoprotein levels, and lower high-density lipoprotein levels. Conclusions: The significant difference in CRP cutoff values in predicting severity between patients with HLAP and NHLAP should be noted in the clinic.

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出版当年[2013]版:
大类 | 3 区 医学
小类 | 3 区 胃肠肝病学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
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出版当年[2012]版:
Q2 GASTROENTEROLOGY & HEPATOLOGY
最新[2023]版:
Q3 GASTROENTEROLOGY & HEPATOLOGY

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第一作者机构: [1]Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai [2]Department of Gastroenterology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province
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通讯机构: [*1]Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, 301 Yanchang Road, Shanghai 200072, People’s Republic of China [*2]Department of Gastroenterology, The First People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200431, People’s Republic of China
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