机构：[1]Molecular Medicine Center, The Second Affiliated Hospital of Suzhou University, Suzhou, Jiangsu 215004, China[2]Biotecan Center of Molecular Medicine, Shanghai, China[3]SNP Institute, Nanhua University, Hengyang, Hunan, China[4]Department of Pathology, City of Hope National Medical Center, City of Hope, Duarte, CA 91010, USA[5]Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA[6]Institute of Pharmacology of Sherbrooke, Quebec, Canada
We propose a short definition of GENOME: The full complement of genetic materials possessed by an intracellular parasite, a cell, or an organism. Accordingly, the human genome is the entire complement of inherited genetic materials possessed by an individual person, or possessed by a cell in an individual person. For higher species, the genomic makeup includes DNA in the nucleus and in the organelles regardless of the number of chromosomes and the homoplasmic or heteroplasmic status of the mitochondrial or chloroplastic DNA. Practically, GENOME can be referred to at the molecular, cellular, individual, and species levels, which has various implications in biotechnological research and molecular diagnostics.
基金：
a combined grant from the Hunan Provincial grant (04A048) and
Chinese Education Ministry (205106), and a Chinese National 863
Major grant (2007AA02Z4A7).
第一作者机构：[1]Molecular Medicine Center, The Second Affiliated Hospital of Suzhou University, Suzhou, Jiangsu 215004, China[2]Biotecan Center of Molecular Medicine, Shanghai, China[3]SNP Institute, Nanhua University, Hengyang, Hunan, China
共同第一作者：
通讯作者：
通讯机构：[1]Molecular Medicine Center, The Second Affiliated Hospital of Suzhou University, Suzhou, Jiangsu 215004, China
推荐引用方式(GB/T 7714)：
Li Xiao,Juan-Sebastian Saldivar,Cuilan Zhou,et al.The Updated Concept of Genome and Its Implications in Biotechnological Research and Molecular Diagnostics[J].MOLECULAR BIOTECHNOLOGY.2009,41(2):152-6.doi:10.1007/s12033-008-9105-0.
APA：
Li Xiao,Juan-Sebastian Saldivar,Cuilan Zhou,Chengli Chen,Jia Zhang...&Kai Li.(2009).The Updated Concept of Genome and Its Implications in Biotechnological Research and Molecular Diagnostics.MOLECULAR BIOTECHNOLOGY,41,(2)
MLA：
Li Xiao,et al."The Updated Concept of Genome and Its Implications in Biotechnological Research and Molecular Diagnostics".MOLECULAR BIOTECHNOLOGY 41..2(2009):152-6
