机构：[1]State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China[2]The Innovation Center of Excellence on Brain Science, Chinese Academy of Sciences, Beijing, China[3]Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA[4]Department ofMedicine, University of California, Los Angeles, CA, USA[5]University of Chinese Academy of Sciences, Beijing, China[6]Department of Radiology, Chaoyang Hospital, Capital Medical University, Beijing, China[7]Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China[8]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China放射科首都医科大学宣武医院[9]Departments of Medicine and Bioengineering, University of California, Los Angeles, CA, United States
ObjectivesThe objective of this study was to explore the feasibility of using intracranial T1-weighted vessel wall imaging (VWI) to visualize the lenticulostriate arteries (LSAs) at 3T.Material and methodsThirteen healthy volunteers were examined with VWI at 3T and TOF-MRA at 7T during the same day. On the vascular skeletons obtained by manual tracing, the number of stems and branches of LSAs were counted. On the most prominent branch in every hemisphere, the contrast-to-noise ratio (CNR), the full length and the local length (5-15 mm above MCAs) were measured and compared between the two methods. Nine stroke patients with intracranial artery stenosis were also recruited into the study. The branches of LSAs were compared between the symptomatic and asymptomatic side.ResultsThe extracted vascular trees were in good agreement between 7T TOF-MRA and 3T VWI. The two acquisitions showed similar numbers of the LSA stems. The number ofbranches revealed by 3T VWI was slightly lower than 7T TOF. The full lengths were slightly lower by VWI at 3T (p = 0.011, ICC = 0.917). The measured local lengths (5-15 mm from MCAs) showed high coherence between VWI and TOF-MRA (p = 0.098, ICC = 0.970). In stroke patients, 12 plaques were identified on MCA segments, and nine plaques were located on the symptomatic side. The average numbers of LSA visualized by 3T VWI were 4.31.3 on the symptomatic side and 5.01.1 on the asymptomatic side.Conclusion3T VWI is capable of depicting LSAs, particularly the stems and the proximal segments, with comparable image quality to that of 7T TOF-MRA.
基金：
This study has received funding by Beijing Municipal Natural
Science Foundation (7184226), Young Elite Scientists Sponsorship
Program by CAST (2017QNRC001), Ministry of Science and
Technology of China grant (2015CB351701), National Science
Foundation of China (NSFC 91749127), American Heart Association
(15SDG25710441), and National Institutes of Health (NHLBI
2R01HL096119).
第一作者机构：[1]State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China[2]The Innovation Center of Excellence on Brain Science, Chinese Academy of Sciences, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[3]Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA[8]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China
推荐引用方式(GB/T 7714)：
Zihao Zhang,Zhaoyang Fan,Qingle Kong,et al.Visualization of the lenticulostriate arteries at 3T using black-blood T1-weighted intracranial vessel wall imaging: comparison with 7T TOF-MRA[J].EUROPEAN RADIOLOGY.2019,29(3):1452-1459.doi:10.1007/s00330-018-5701-y.
APA：
Zihao Zhang,Zhaoyang Fan,Qingle Kong,Jiayu Xiao,Fang Wu...&Yan Zhuo.(2019).Visualization of the lenticulostriate arteries at 3T using black-blood T1-weighted intracranial vessel wall imaging: comparison with 7T TOF-MRA.EUROPEAN RADIOLOGY,29,(3)
MLA：
Zihao Zhang,et al."Visualization of the lenticulostriate arteries at 3T using black-blood T1-weighted intracranial vessel wall imaging: comparison with 7T TOF-MRA".EUROPEAN RADIOLOGY 29..3(2019):1452-1459
医学