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Magnetic resonance multitasking for motion-resolved quantitative cardiovascular imaging

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机构： [1]Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. [2]Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. [3]Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA. [4]Department of Radiology, Xuanwu Hospital, Beijing, China. [5]Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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Quantitative cardiovascular magnetic resonance (CMR) imaging can be used to characterize fibrosis, oedema, ischaemia, inflammation and other disease conditions. However, the need to reduce artefacts arising from body motion through a combination of electrocardiography (ECG) control, respiration control and contrast-weighting selection makes CMR exams lengthy. Here, we show that physiological motions and other dynamic processes can be conceptualized as multiple time dimensions that can be resolved via low-rank tensor imaging, allowing for motion-resolved quantitative imaging with up to four time dimensions. This continuous-acquisition approach, which we name CMR multitasking, captures-rather than avoids-motion, relaxation and other dynamics to efficiently perform quantitative CMR without the use of ECG triggering or breath holds. We demonstrate that CMR multitasking allows for T-1 mapping, T-1/T-2 mapping and time-resolved T-1 mapping of myocardial perfusion without ECG information and/or under free-breathing conditions. CMR multitasking may provide a foundation for the development of setup-free CMR imaging for the quantitative evaluation of cardiovascular health.

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大类 | 1 区

医学

小类 | 1 区工程：生物医学

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出版当年[2016]版：

无

最新[2023]版：

Q1 ENGINEERING, BIOMEDICAL

影响因子： 27.7 最新[2023版] 29.6 最新五年平均 0 出版当年[2016版] 0 出版当年五年平均 0 出版前一年[2015版]

第一作者：

第一作者机构： [1]Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. [2]Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

通讯作者：

通讯机构： [1]Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. [3]Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.

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