机构：[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China神经内科首都医科大学宣武医院[b]Beijing Key Laboratory of Geriatric Cognitive Disorders, Beijing, China[c]Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China[d]Key Laboratory of Neurodegenerative Diseases, Ministry of Education, Beijing, China[e]National Clinical Research Center for Geriatric Disorders, Beijing, China[f]Department of Neurology, Shandong Provincial Hospital, Shandong University, Jinan, China[g]Department of Neurology, Henan Provincial People’s Hospital, Zhengzhou, China[h]Department of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, China[i]Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, China[j]Dementia Unit, Beijing Geriatric Hospital, Beijing, China[k]Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China[l]Department of Neurology, Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, China[m]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China[n]Department of Gerontology, Fuxing Hospital, Capital Medical University, Beijing, China[o]Department of Psychiatry, Zhejiang Provincial People’s Hospital, Hangzhou, China[p]Department of Neurology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China[q]Department of Neurology, Daping Hospital, Third Military Medical University, Chongqing, China[r]Department of Neurology, Daqing Oilfield General Hospital, Daqing, China[s]Department of Neurology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China[t]Department of Neurology and Institute of Neurology, Huashan Hospital Fudan University, Shanghai, China[u]Department of Neurology, Baotou Central Hospital, Baotou, China[v]Department of Neurology, The 88th Hospital of PLA, Taian, China[w]Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, China[x]Department of Neurology, Xiangya Hospital Central South University, Changsha, China[y]Department of Neurology, People’s Hospital of Jiangxi Province, Nanchang, China[z]Department of Neurology, Weihai Municipal Hospital, Weihai, China[aa]Department of Neurology, Center for Geriatric Medicine, China-Japan Friendship Hospital, Beijing, China[ab]Department of Geriatric Psychiatric, Guangzhou Huiai Hospital, Guangzhou, China[ac]Department of Neurology, Hebei General Hospital, Shijiazhuang, China[ad]Department of Neurology, Beijing Rehabilitation Hospital Affiliated to Capital Medical University, Beijing, China[ae]Department of Neurology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China[af]Department of Neurology, Henry Ford Hospital, Detroit, MI, USA[ag]McGill Centre for Studies in Aging, McGill University, Montreal, Canada
Introduction: The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain. Methods: We collected data from 3098 patients with AD in 81 representative centers across China and estimated AD costs for individual patient and total patients in China in 2015. Based on this data, we re-estimated the worldwide costs of AD. Results: The annual socioeconomic cost per patient was US $19,144.36, and total costs were US $167.74 billion in 2015. The annual total costs are predicted to reach US $507.49 billion in 2030 and US $1.89 trillion in 2050. Based on our results, the global estimates of costs for dementia were US $957.56 billion in 2015, and will be US $2.54 trillion in 2030, and US $9.12 trillion in 2050, much more than the predictions by the World Alzheimer Report 2015. Discussion: China bears a heavy burden of AD costs, which greatly change the estimates of AD cost worldwide. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
基金：
CHINA-CANADA Joint Initiative on Alzheimer's Disease and Related Disorders [81261120571]; Key Project of the National Natural Science Foundation of China [81530036]; National Key Scientific Instrument and Equipment Development Project [31627803]; Key Medical Professional Development Plan of Beijing Municipal Administration of Hospitals [ZY201301]; Mission Program of Beijing Municipal Administration of Hospitals [SML20150801]; Beijing Scholars Program, Beijing Municipal Commission of Health and Family Planning [PXM2017_026283_000002]; Beijing Brain Initiative from Beijing Municipal Science & Technology Commission [Z161100000216137]
第一作者机构：[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China[b]Beijing Key Laboratory of Geriatric Cognitive Disorders, Beijing, China[c]Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China[d]Key Laboratory of Neurodegenerative Diseases, Ministry of Education, Beijing, China[e]National Clinical Research Center for Geriatric Disorders, Beijing, China
通讯作者：
通讯机构：[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China[b]Beijing Key Laboratory of Geriatric Cognitive Disorders, Beijing, China[c]Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China[d]Key Laboratory of Neurodegenerative Diseases, Ministry of Education, Beijing, China[e]National Clinical Research Center for Geriatric Disorders, Beijing, China[ag]McGill Centre for Studies in Aging, McGill University, Montreal, Canada
推荐引用方式(GB/T 7714)：
Jianping Jia,Cuibai Wei,Shuoqi Chen,et al.The cost of Alzheimer's disease in China and re-estimation of costs worldwide[J].ALZHEIMERS & DEMENTIA.2018,14(4):483-491.doi:10.1016/j.jalz.2017.12.006.
APA：
Jianping Jia,Cuibai Wei,Shuoqi Chen,Fangyu Li,Yi Tang...&Serge Gauthier.(2018).The cost of Alzheimer's disease in China and re-estimation of costs worldwide.ALZHEIMERS & DEMENTIA,14,(4)
MLA：
Jianping Jia,et al."The cost of Alzheimer's disease in China and re-estimation of costs worldwide".ALZHEIMERS & DEMENTIA 14..4(2018):483-491
医学