机构:[1]Department of Ultrasound, Xuanwu Hospital, Capital Medical University, Beijing, PR China首都医科大学宣武医院[2]Department of Surgery, Xuanwu Hospital, Capital Medical University, Beijing, PR China首都医科大学宣武医院[3]Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, PR China病理科首都医科大学宣武医院
Background: Accurate diagnosis of papillary thyroid microcarcinoma (PTMC) is important for further management. Ultrasound (US) is the most frequently used imaging modality for PTMC. Purpose: To evaluate the diagnostic value of conventional US, contrast-enhanced ultrasound (CEUS) and real-time elastography (RTE) for patients with PTMC. Material and Methods: In total, 135 patients with subcentimeter thyroid nodules who underwent conventional US, CEUS, and RTE before surgery were enrolled. A multivariate logistic regression analysis was performed to assess the independent predictors of PTMC. The diagnostic performances of conventional US, CEUS, and RTE were evaluated with a receiver operating characteristic (ROC) curve analysis. Results: A taller-than-wide shape was identified as the strongest predictor of PTMC (odds ratio [OR], 25.21), followed by heterogeneous enhancement (OR, 24.03), marked hypoechogenicity (OR, 21.71), poorly defined margin (OR, 5.51), strain ratio (OR, 2.59), and age (OR, 0.92; all P values < 0.05). Heterogeneous enhancement on CEUS showed the highest positive predictive value (PPV; 88.0%) and an accuracy of 83.7%. A logistic regression model was created to predict PTMC using conventional US, CEUS, and RTE. The area under the ROC curve was 0.97, with a sensitivity of 88.6% and a specificity of 94.6%. Conclusion: Conventional US combined with CEUS and RTE can improve the diagnostic accuracy of PTMC.
基金:
Public Health Project in the Capital (Grant no. Z161100000116060) of Beijing Municipal Science and Technology Commission.
第一作者机构:[1]Department of Ultrasound, Xuanwu Hospital, Capital Medical University, Beijing, PR China
共同第一作者:
通讯作者:
通讯机构:[*1]Department of Ultrasound, Xuanwu Hospital, Capital Medical University, 45 Changchun Rd, 100053 Beijing, PR China.
推荐引用方式(GB/T 7714):
Hui Juan Ma,Jing Chun Yang,Zhen Peng Leng,et al.Preoperative prediction of papillary thyroid microcarcinoma via multiparameter ultrasound[J].ACTA RADIOLOGICA.2017,58(11):1303-1311.doi:10.1177/0284185117692167.
APA:
Hui Juan Ma,Jing Chun Yang,Zhen Peng Leng,Ying Chang,Hua Kang&Liang Hong Teng.(2017).Preoperative prediction of papillary thyroid microcarcinoma via multiparameter ultrasound.ACTA RADIOLOGICA,58,(11)
MLA:
Hui Juan Ma,et al."Preoperative prediction of papillary thyroid microcarcinoma via multiparameter ultrasound".ACTA RADIOLOGICA 58..11(2017):1303-1311