机构：[1]Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China神经外科首都医科大学宣武医院[2]Beijing Institute of Functional Neurosurgery, Beijing, China
ObjectiveTo investigate the effect of motor cortex stimulation (MCS) on central poststroke pain (CPSP) and the outcome predictors associated with medium- to long-term results. Materials and MethodsThis is a retrospective review of 16 CPSP patients treated with MCS with a mean follow-up of 28.2 months. The pain intensity was assessed based on the visual analogue scale (VAS) before surgery and at various follow-up visits. An effective outcome was determined to be at least 40% pain relief. The type (hemorrhage or ischemia) and location (thalamus or non-thalamus) of the stroke, the location of the electrode (epidural or subdural), and preoperative repetitive transcranial magnetic stimulation (rTMS) results were analyzed to evaluate whether they are predictive of effective outcomes. ResultsThe mean VAS before surgery was 8.00.7 compared with 3.8 +/- 2.1 one month after surgery and 5.3 +/- 2.4 at the last follow-up. There were no differences in the analgesic effects between the types of stroke (hemorrhage or ischemia), stroke location (thalamus or non-thalamus), or the location of the electrode (epidural or subdural). The association between preoperative rTMS and effective outcomes was significant with a positive predictive value of 0.8571 and a negative predictive value of 0.7778. ConclusionsOur results suggest that MCS significantly reduces the pain intensity of CPSP. The types of stroke (hemorrhage or ischemia), stroke location (thalamus or nonthalamus), and the location of the electrode (epidural or subdural) were not significant predictors of the analgesic effects of MCS. Preoperative rTMS might be helpful for screening candidates for MCS.
基金：
Beijing Science and Technology Rising Star Program (2003B35);
The high-level health technicians training program of Beijing health system (2009-3-60);
The Ministry of Science and Technology of China grant (2012CB825505).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2016]版：
大类|3 区医学
小类|3 区临床神经病学4 区医学：研究与实验
最新[2023]版：
大类|3 区医学
小类|3 区临床神经病学3 区医学：研究与实验
JCR分区：
出版当年[2015]版：
Q2MEDICINE, RESEARCH & EXPERIMENTALQ2CLINICAL NEUROLOGY
最新[2023]版：
Q2CLINICAL NEUROLOGYQ2MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构：[1]Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China[2]Beijing Institute of Functional Neurosurgery, Beijing, China
通讯作者：
通讯机构：[*1]Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University,Beijing Institute of Functional Neurosurgery, No. 45 Changchun Street, Xicheng District, Beijing, China
推荐引用方式(GB/T 7714)：
Xiaolei Zhang,Yongsheng Hu ,Wei Tao,et al.The Effect of Motor Cortex Stimulation on Central Poststroke Pain in a Series of 16 Patients With a Mean Follow-Up of 28 Months[J].NEUROMODULATION.2017,20(5):492-496.doi:10.1111/ner.12547.
APA：
Xiaolei Zhang,Yongsheng Hu,,Wei Tao,Hongwei Zhu,Dongsheng Xiao&Yongjie Li.(2017).The Effect of Motor Cortex Stimulation on Central Poststroke Pain in a Series of 16 Patients With a Mean Follow-Up of 28 Months.NEUROMODULATION,20,(5)
MLA：
Xiaolei Zhang,et al."The Effect of Motor Cortex Stimulation on Central Poststroke Pain in a Series of 16 Patients With a Mean Follow-Up of 28 Months".NEUROMODULATION 20..5(2017):492-496
