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Association between glycemic variability and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with acute coronary syndrome during 30-day follow-up

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收录情况： ◇ SCIE

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机构： [1]Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

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关键词： Glucose fluctuation Diabetes mellitus MACCE Acute coronary syndrome

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Background: We explored the association between glycemic variability and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with acute coronary syndrome (ACS) during 30-day follow-up. Methods: From May 2013 to April 2015, a total of 864 patients with ACS were divided to high glycemic variability group (H group) (n = 285) and low glycemic variability group (L group) (n = 579). The primary end point was a 30-day incidence of MACCE. Secondary end points were the incidence of atrial fibrillation (AF) during hospitalization and length of hospital stay. Results: The primary end point occurred in 15.2% of patients in H group and in 9.7% in L group (p = 0.03). The incidence of AF during hospitalization was 14.5% in H group and 8.9% in L group (p = 0.02). Compared with the L group, the H group extended the length of hospital stay. Multivariable analysis suggested that high glycemic variability conferred a 57% risk increment of 30-day MACCE (odds ratio 1.97, 95% confidence interval 1.32-6.86; p = 0.02). Conclusion: The trial shows that higher blood glucose variability was correlated with higher incidence of MACCE, AF and longer length of stay. (C) 2017 Published by Elsevier B.V.

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出版当年[2016]版：

大类 | 3 区医学

小类 | 2 区医学实验技术

最新[2023]版：

大类 | 3 区医学

小类 | 3 区医学实验技术

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出版当年[2015]版：

Q1 MEDICAL LABORATORY TECHNOLOGY

最新[2023]版：

Q2 MEDICAL LABORATORY TECHNOLOGY

影响因子： 3.2 最新[2023版] 3.7 最新五年平均 2.799 出版当年[2015版] 2.892 出版当年五年平均 2.824 出版前一年[2014版] 2.873 出版后一年[2016版]

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第一作者机构： [1]Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

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通讯作者：

通讯机构： [1]Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

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