We investigated the association between mean platelet volume (MPV) and risk of all-cause mortality in Chinese patients with ST-Elevation Myocardial Infarction (STEMI). We enrolled 1836 patients with STEMI in Xuanwu Hospital from January 2008 to December 2013. Based on MPV, patients were categorized into the following groups: < 9.5 fL (n = 85), 9.5-11.0 fL (n = 776), 11.1-12.5 fL (n = 811) and. 12.5 fL (n = 164), respectively. Mean duration of follow-up was 56.9 months, and 197 patients (10.7%) died during follow-up. All-cause mortality rates were compared between groups. The lowest mortality occurred in patients with MPV between 9.5-11.0 fL, with a multivariable-adjusted hazard ratio (HR) of 1.15(95% CI 0.62-1.50), 1.38(95% CI 1.20-1.68), and 1.72(95% CI 1.41-1.96) in patients with MPV of. 9.5, 11.1-12.5 and. 12.5 fL, respectively. Therefore, increased MPV was associated with all-cause mortality in Chinese patients with STEMI. MPV might be useful as a marker for risk stratification in Chinese patients with STEMI.
基金：
National Program on Key Basic Research Project (973 Program) [2012CB517802]
第一作者机构：[1]Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, China, 100053.
通讯作者：
通讯机构：[1]Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing, China, 100053.
推荐引用方式(GB/T 7714)：
Xi-peng Sun,Bo-yu Li,Jing Li,et al.Impact of Mean Platelet Volume on Long-Term Mortality in Chinese Patients with ST-Elevation Myocardial Infarction[J].SCIENTIFIC REPORTS.2016,6:doi:10.1038/srep21350.
APA：
Xi-peng Sun,Bo-yu Li,Jing Li,Wei-wei Zhu&Qi Hua.(2016).Impact of Mean Platelet Volume on Long-Term Mortality in Chinese Patients with ST-Elevation Myocardial Infarction.SCIENTIFIC REPORTS,6,
MLA：
Xi-peng Sun,et al."Impact of Mean Platelet Volume on Long-Term Mortality in Chinese Patients with ST-Elevation Myocardial Infarction".SCIENTIFIC REPORTS 6.(2016)
