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Association between Carotid Intima-Media Thickness and Cognitive Impairment in a Chinese Stroke Population: A Cross-sectional Study

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机构: [1]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China. [2]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. [3]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China. [4]Department of Neurology, The First Affiliated Hospital, Zhejiang University, Zhejiang, China. [5]Department of Neurology, Shanxi People’s Hospital, Shanxi Medical University, Shanxi, China. [6]Department of Neurology, The Third Hospital of Shijiazhuang, Shijiazhuang, China. [7]Department of Neurology, The First Affiliated Hospital of Xi’an Jiao Tong University, Xian, China. [8]Department of Neurology, The First Affiliated Hospital of Xinxiang Medical College, Xinxiang, China. [9]Department of Neurology, Guizhou People’s Hospital, Guizhou, China. [10]Department of Inspection, Guizhou People’s Hospital, Guizhou, China. [11]Department of Traditional Chinese Medicine, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China.
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This study aimed to investigate the potential associations between carotid intima-media thickness and cognitive impairment among patients with acute ischemic stroke and to identify the clinical implications. We measured carotid intima-media thickness (IMT) and performed the Mini-Mental State Examination (MMSE) upon the admission of 1,826 acute ischemic stroke patients. The association between IMT and cognitive impairment evaluated by the MMSE was assessed with a multivariate regression analysis. Other clinical variables of interest were also assessed. After adjusting for potential confounders, participants in the highest IMT quartile had a higher likelihood of having cognitive impairments compared with the lowest IMT quartile (odds ratio: 3.01, 95% confidence interval: 2.07-4.37, p < 0.001). Stratified analyses indicated that this positive correlation was similar for the maxIMT and mean IMT of carotid artery measurements. A positive correlation was found between IMT and cognitive impairment in participants with acute ischemic stroke.

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出版当年[2015]版:
大类 | 2 区 综合性期刊
小类 | 2 区 综合性期刊
最新[2023]版:
大类 | 2 区 综合性期刊
小类 | 2 区 综合性期刊
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出版当年[2014]版:
Q1 MULTIDISCIPLINARY SCIENCES
最新[2023]版:
Q1 MULTIDISCIPLINARY SCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [1]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
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通讯机构: [1]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China. [11]Department of Traditional Chinese Medicine, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China.
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