机构:[1]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.[2]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.[3]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.[4]Department of Neurology, The First Affiliated Hospital, Zhejiang University, Zhejiang, China.[5]Department of Neurology, Shanxi People’s Hospital, Shanxi Medical University, Shanxi, China.[6]Department of Neurology, The Third Hospital of Shijiazhuang, Shijiazhuang, China.[7]Department of Neurology, The First Affiliated Hospital of Xi’an Jiao Tong University, Xian, China.[8]Department of Neurology, The First Affiliated Hospital of Xinxiang Medical College, Xinxiang, China.[9]Department of Neurology, Guizhou People’s Hospital, Guizhou, China.[10]Department of Inspection, Guizhou People’s Hospital, Guizhou, China.[11]Department of Traditional Chinese Medicine, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China.首都医科大学宣武医院
This study aimed to investigate the potential associations between carotid intima-media thickness and cognitive impairment among patients with acute ischemic stroke and to identify the clinical implications. We measured carotid intima-media thickness (IMT) and performed the Mini-Mental State Examination (MMSE) upon the admission of 1,826 acute ischemic stroke patients. The association between IMT and cognitive impairment evaluated by the MMSE was assessed with a multivariate regression analysis. Other clinical variables of interest were also assessed. After adjusting for potential confounders, participants in the highest IMT quartile had a higher likelihood of having cognitive impairments compared with the lowest IMT quartile (odds ratio: 3.01, 95% confidence interval: 2.07-4.37, p < 0.001). Stratified analyses indicated that this positive correlation was similar for the maxIMT and mean IMT of carotid artery measurements. A positive correlation was found between IMT and cognitive impairment in participants with acute ischemic stroke.
基金:
the China Stroke Prevention Project of the National Health and Family Planning Commission.
第一作者机构:[1]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
共同第一作者:
通讯作者:
通讯机构:[1]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.[11]Department of Traditional Chinese Medicine, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China.
推荐引用方式(GB/T 7714):
Wei Yue,Anxin Wang,Hui Liang,et al.Association between Carotid Intima-Media Thickness and Cognitive Impairment in a Chinese Stroke Population: A Cross-sectional Study[J].SCIENTIFIC REPORTS.2016,6:-.doi:10.1038/srep19556.
APA:
Wei Yue,Anxin Wang,Hui Liang,Fengyun Hu,Yunshu Zhang...&Yong Ji.(2016).Association between Carotid Intima-Media Thickness and Cognitive Impairment in a Chinese Stroke Population: A Cross-sectional Study.SCIENTIFIC REPORTS,6,
MLA:
Wei Yue,et al."Association between Carotid Intima-Media Thickness and Cognitive Impairment in a Chinese Stroke Population: A Cross-sectional Study".SCIENTIFIC REPORTS 6.(2016):-