Coronary Plaque Characteristics Assessed by 256-Slice Coronary CT Angiography and Association with High-Sensitivity C-Reactive Protein in Symptomatic Patients with Type 2 Diabetes
机构：[1]Department of CT, The Second Affiliated Hospital of HarbinMedicalUniversity, Harbin 150086, China[2]Department of Radiology, Xuanwu Hospital, Beijing 100053, China放射科首都医科大学宣武医院[3]Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Little is known regarding plaque distribution, composition, and the association with inflammation in type 2 diabetes mellitus (DM2). This study aimed to assess the relationship between coronary plaque subtypes and high-sensitivity C-reactive protein levels. Coronary CTA were performed in 98 symptomatic DM2 patients and 107 non-DM2 patients using a 256-slice CT. The extent and types of plaque as well as luminal narrowing were evaluated. Patients with DM2 were more likely to have significant stenosis (>50%) with calcified plaques in at least one coronary segment (p < 0.01); the prevalence rates of diffuse calcified plaques in the DM2 and non-DM2 groups were 31.6% and 4.7%, respectively (p < 0.01). Plasma hs-CRP levels in DM2 with calcified plaques were higher compared with values obtained for the non-DM2 group (p < 0.01). In conclusion, combination of coronary CTA and hs-CRP might improve risk stratification in symptomatic DM2 patients.
基金：
National Science Foundation of China (nos. 81322022 and 81561130163).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2015]版：
大类|3 区医学
小类|3 区内分泌学与代谢3 区医学：研究与实验
最新[2025]版：
大类|3 区医学
小类|3 区内分泌学与代谢3 区医学：研究与实验
JCR分区：
出版当年[2014]版：
Q3MEDICINE, RESEARCH & EXPERIMENTALQ3ENDOCRINOLOGY & METABOLISM
最新[2023]版：
Q2ENDOCRINOLOGY & METABOLISMQ2MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构：[1]Department of CT, The Second Affiliated Hospital of HarbinMedicalUniversity, Harbin 150086, China
通讯作者：
通讯机构：[2]Department of Radiology, Xuanwu Hospital, Beijing 100053, China[3]Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
推荐引用方式(GB/T 7714)：
Jinling Zhang ,Zhehao Lv ,Deli Zhao ,et al.Coronary Plaque Characteristics Assessed by 256-Slice Coronary CT Angiography and Association with High-Sensitivity C-Reactive Protein in Symptomatic Patients with Type 2 Diabetes[J].JOURNAL OF DIABETES RESEARCH.2016,2016:doi:10.1155/2016/4365156.
APA：
Jinling Zhang,,Zhehao Lv,,Deli Zhao,,Lili Liu,,Yong Wan,...&Qi Yang.(2016).Coronary Plaque Characteristics Assessed by 256-Slice Coronary CT Angiography and Association with High-Sensitivity C-Reactive Protein in Symptomatic Patients with Type 2 Diabetes.JOURNAL OF DIABETES RESEARCH,2016,
MLA：
Jinling Zhang,,et al."Coronary Plaque Characteristics Assessed by 256-Slice Coronary CT Angiography and Association with High-Sensitivity C-Reactive Protein in Symptomatic Patients with Type 2 Diabetes".JOURNAL OF DIABETES RESEARCH 2016.(2016)
