机构:[1]Department of Radiology, Southwest Hospital,Third Military Medical University, Chongqing 400038, China[2]Department of Endocrinology, Southwest Hospital,Third Military Medical University, Chongqing 400038, China[3]Department of Radiology, Xuanwu Hospital, Beijing 100053, China放射科首都医科大学宣武医院
Background. Diabetic cardiomyopathy (DCM) is always accompanied with alteration of left ventricular structure and function. The aims of this study were to assess the structural remodelling in patients with DCM by cardiovascular magnetic resonance (CMR) and correlation of structural remodelling with severity of DCM. Methods. Twenty-five patients (53.8 +/- 8.8 years, 52.0% males) with DCM and thirty-one normal healthy controls (51.9 +/- 13.6 years, 45.2% males) were scanned by CMR cine to assess function and structure of left ventricular. Length of diabetic history and results of cardiac echocardiography (E', A', and E'/A') were also measured. Results. Compared with normal controls group, DCM group was associated with significantly increased ratio of left ventricular mass at end diastole to end-diastolic volume (MVR) (P < 0.05) and no significant difference was in mass at end diastole (P > 0.05). The ratio correlated with both length of diabetic history and echocardiographic Doppler tissue imaging E' (all P < 0.05). Conclusions. CMR can be a powerful technique to assess LV remodelling, and MVR may be considered as an imaging marker to evaluate the severity of LV remodelling in patients with DCM.
基金:
the National Natural Science Foundation of China (no. 81471647)
the National Natural Science Foundation of China (no. 81571748).
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2015]版:
大类|3 区医学
小类|3 区内分泌学与代谢3 区医学:研究与实验
最新[2023]版:
大类|3 区医学
小类|3 区内分泌学与代谢3 区医学:研究与实验
JCR分区:
出版当年[2014]版:
Q3MEDICINE, RESEARCH & EXPERIMENTALQ3ENDOCRINOLOGY & METABOLISM
最新[2023]版:
Q2ENDOCRINOLOGY & METABOLISMQ2MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构:[1]Department of Radiology, Southwest Hospital,Third Military Medical University, Chongqing 400038, China
通讯作者:
通讯机构:[1]Department of Radiology, Southwest Hospital,Third Military Medical University, Chongqing 400038, China[2]Department of Endocrinology, Southwest Hospital,Third Military Medical University, Chongqing 400038, China
推荐引用方式(GB/T 7714):
Yongning Shang,Xiaochun Zhang,Liu Chen ,et al.Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance[J].JOURNAL OF DIABETES RESEARCH.2016,2016:doi:10.1155/2016/4786925.
APA:
Yongning Shang,Xiaochun Zhang,Liu Chen,,Weiling Leng,,Xiaotian Lei,...&JianWang.(2016).Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance.JOURNAL OF DIABETES RESEARCH,2016,
MLA:
Yongning Shang,et al."Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance".JOURNAL OF DIABETES RESEARCH 2016.(2016)