In recent years, the correlation between aortic atheroma (AA) and the occurrence and recurrence of ischemic cerebrovascular disease (ICVD) has attracted much attention, but the contributory mechanisms remain controversial. This review analyzes related research on the roles of AA in ICVD, and demonstrates the correlation between the formation and development of AA and abnormal metabolism, inflammation, hemodynamic changes, and other contributory factors. The presence of complex aortic plaque (CAP) in the ascending aorta and aortic arch increases the risk of cerebral embolism and degree of injury, while the association between CAP in the descending aorta and cerebral embolism remains ambiguous. AA also functions as an indicator of atherosclerosis burden as well as hypercoagulability, which may further increase the risk of ICVD. Further study on the relationship of AA to ICVD will improve diagnosis and treatment in clinical practice. (C) 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.
第一作者机构：[1]the Department of Neurology, Xuanwu Hospital, the Capital Medical University, Beijing, China.
通讯作者：
通讯机构：[*1]Department of Neurology, Xuanwu Hospital, the Capital Medical University, 45 Changchun Street, Beijing, China.
推荐引用方式(GB/T 7714)：
Qi Kong ,Xin Ma .Contributing Mechanisms of Aortic Atheroma in Ischemic Cerebrovascular Disease[J].JOURNAL OF STROKE & CEREBROVASCULAR DISEASES.2015,24(12):2653-2659.doi:10.1016/j.jstrokecerebrovasdis.2015.09.033.
APA：
Qi Kong,&Xin Ma,.(2015).Contributing Mechanisms of Aortic Atheroma in Ischemic Cerebrovascular Disease.JOURNAL OF STROKE & CEREBROVASCULAR DISEASES,24,(12)
MLA：
Qi Kong,,et al."Contributing Mechanisms of Aortic Atheroma in Ischemic Cerebrovascular Disease".JOURNAL OF STROKE & CEREBROVASCULAR DISEASES 24..12(2015):2653-2659
