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A rare case of nonenhancing primary central nervous system lymphoma mimic multiple sclerosis

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机构: [1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, People’s Republic of China.
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摘要:
Primary central nervous system lymphoma (PCNSL) is reported to have increased in the last decades. Early diagnosis is crucial for proper management of this tumor. We report a case of a 48-year-old man who was initially diagnosed with multiple sclerosis. Magnetic resonance imaging of the brain revealed multiple lesions with hypersignals in the bilateral basal ganglia and brain stem in T2-weighted image and non-enhancement, while positron emission tomography showed a low uptake of F-18-fluorodeoxyglucose in the affected brain, indicative of demyelination. However, this individual was correctly diagnosed with PCNSL after biopsy and further histological analysis. Primary central nervous system lymphoma must be considered even when nonenhancing, diffuse lesions are seen on MRI. A visible tumor on imaging is essential to ensure an early brain biopsy and histological diagnosis.

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出版当年[2014]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学
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出版当年[2013]版:
Q4 CLINICAL NEUROLOGY
最新[2023]版:
Q4 CLINICAL NEUROLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2013版] 出版当年五年平均 出版前一年[2012版] 出版后一年[2014版]

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第一作者机构: [1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, People’s Republic of China.
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通讯机构: [*1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing 100053, People’s Republic of China.
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