Primary central nervous system lymphoma (PCNSL) is reported to have increased in the last decades. Early diagnosis is crucial for proper management of this tumor. We report a case of a 48-year-old man who was initially diagnosed with multiple sclerosis. Magnetic resonance imaging of the brain revealed multiple lesions with hypersignals in the bilateral basal ganglia and brain stem in T2-weighted image and non-enhancement, while positron emission tomography showed a low uptake of F-18-fluorodeoxyglucose in the affected brain, indicative of demyelination. However, this individual was correctly diagnosed with PCNSL after biopsy and further histological analysis. Primary central nervous system lymphoma must be considered even when nonenhancing, diffuse lesions are seen on MRI. A visible tumor on imaging is essential to ensure an early brain biopsy and histological diagnosis.
第一作者机构:[1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, People’s Republic of China.
通讯作者:
通讯机构:[*1]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing 100053, People’s Republic of China.
推荐引用方式(GB/T 7714):
Hai Chen ,Huiqing Dong .A rare case of nonenhancing primary central nervous system lymphoma mimic multiple sclerosis[J].NEUROSCIENCES.2015,20(4):380-384.doi:10.17712/nsj.2015.4.20150125.
APA:
Hai Chen,&Huiqing Dong,.(2015).A rare case of nonenhancing primary central nervous system lymphoma mimic multiple sclerosis.NEUROSCIENCES,20,(4)
MLA:
Hai Chen,,et al."A rare case of nonenhancing primary central nervous system lymphoma mimic multiple sclerosis".NEUROSCIENCES 20..4(2015):380-384