机构:[1]Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, People’s Republic of China[2]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, Henan, People’s Republic of China神经内科首都医科大学宣武医院
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a new category of autoimmune encephalitis associated with anti-NMDA receptor antibodies. The disease was first described in 2007, and it predominantly affects young women with or without ovarian teratomas. Most patients typically present with seizures, a decreased consciousness level, dyskinesia, autonomic dysfunction, and psychiatric symptoms. The presence of anti-thyroid antibodies in non-tumor-associated anti-NMDA receptor encephalitis was first described in 2010. Additionally, anti-thyroid antibodies were found in teratoma-associated anti-NMDA receptor encephalitis. We report the cases of 3 Chinese girls with non-tumor-associated anti-NMDA receptor encephalitis with positive anti-thyroid antibodies. We followed up the details of their titers and suggest that anti-thyroid antibodies were an indicator of autoimmune predisposition in the development of non-tumor-associated anti-NMDA receptor encephalitis.
基金:
National Natural Science Foundation of China (grant 81201080),
Young foundation of the First Affiliated Hospital of Zhengzhou University.
第一作者机构:[1]Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, People’s Republic of China
通讯作者:
通讯机构:[*1]Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052 Henan, People’s Republic of China.
推荐引用方式(GB/T 7714):
Wenjuan Guan ,Zhenqiang Fu ,Hui Zhang ,et al.Non-tumor-Associated Anti-N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis in Chinese Girls With Positive Anti-thyroid Antibodies[J].JOURNAL OF CHILD NEUROLOGY.2015,30(12):1582-1585.doi:10.1177/0883073815575365.
APA:
Wenjuan Guan,,Zhenqiang Fu,,Hui Zhang,,Lijun Jing,,Jingjing Lu,...&Yanjie Jia,.(2015).Non-tumor-Associated Anti-N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis in Chinese Girls With Positive Anti-thyroid Antibodies.JOURNAL OF CHILD NEUROLOGY,30,(12)
MLA:
Wenjuan Guan,,et al."Non-tumor-Associated Anti-N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis in Chinese Girls With Positive Anti-thyroid Antibodies".JOURNAL OF CHILD NEUROLOGY 30..12(2015):1582-1585