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Non-tumor-Associated Anti-N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis in Chinese Girls With Positive Anti-thyroid Antibodies

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机构: [1]Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, People’s Republic of China [2]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, Henan, People’s Republic of China
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关键词: anti-N-methyl-d-aspartate (NMDA) receptor encephalitis anti-thyroid antibodies chinese adolescents

摘要:
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a new category of autoimmune encephalitis associated with anti-NMDA receptor antibodies. The disease was first described in 2007, and it predominantly affects young women with or without ovarian teratomas. Most patients typically present with seizures, a decreased consciousness level, dyskinesia, autonomic dysfunction, and psychiatric symptoms. The presence of anti-thyroid antibodies in non-tumor-associated anti-NMDA receptor encephalitis was first described in 2010. Additionally, anti-thyroid antibodies were found in teratoma-associated anti-NMDA receptor encephalitis. We report the cases of 3 Chinese girls with non-tumor-associated anti-NMDA receptor encephalitis with positive anti-thyroid antibodies. We followed up the details of their titers and suggest that anti-thyroid antibodies were an indicator of autoimmune predisposition in the development of non-tumor-associated anti-NMDA receptor encephalitis.

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出版当年[2014]版:
大类 | 4 区 医学
小类 | 3 区 儿科 4 区 临床神经病学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 儿科
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出版当年[2013]版:
Q2 PEDIATRICS Q3 CLINICAL NEUROLOGY
最新[2023]版:
Q2 PEDIATRICS Q3 CLINICAL NEUROLOGY

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第一作者机构: [1]Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, People’s Republic of China
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通讯机构: [*1]Department of Neurology, First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052 Henan, People’s Republic of China.
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