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Long-term effects of continuous theta-burst stimulation in visuospatial neglect

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机构: [1]Department of Rehabilitation, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Department of Neurology, Beijing Electric Power Hospital, State Grid Corporation of China, Beijing, China
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关键词: Visuospatial neglect neurorehabilitation repetitive transcranial magnetic stimulation interhemispheric rivalry

摘要:
Objective: To investigate whether the efficacy of continuous theta-burst stimulation (cTBS) for improving visuospatial neglect can be enhanced by providing more days of stimulation and more stimulation trains per day. Methods: In a prospective study, right-handed patients with right hemisphere stroke and visuospatial neglect were randomized to cTBS or sham cTBS treatment for 2 weeks and were followed up for 4 weeks. The cTBS group received active cTBS over the posterior parietal cortex of the unaffected hemisphere, combined with conventional rehabilitation therapy. Changes in scores for two paper-pencil tests for visuospatial neglect (star cancellation and line bisection) were evaluated. Results: In each group, 10 patients completed follow up. Compared with the sham group, star cancellation test scores in the cTBS group were improved by 37.03% at the end of treatment and by 47.21% after 4 weeks' follow up, and the line bisection score improved by 21.37% at the end of treatment and by 35.99% after 4 weeks' follow up. Conclusions: These results suggest that the efficacy of cTBS in visuospatial neglect can be enhanced and prolonged by increasing the days of stimulation and the number of stimulation trains per day over the left posterior parietal cortex.

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出版当年[2014]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
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出版当年[2013]版:
Q4 PHARMACOLOGY & PHARMACY Q4 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL Q4 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均 出版当年[2013版] 出版当年五年平均 出版前一年[2012版] 出版后一年[2014版]

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第一作者机构: [1]Department of Rehabilitation, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Department of Neurology, Beijing Electric Power Hospital, State Grid Corporation of China, Beijing, China
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通讯机构: [*1]Department of Rehabilitation, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing 100053, China.
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