Socioeconomic status in relation to cardiovascular disease and cause-specific mortality: a comparison of Asian and Australasian populations in a pooled analysis
机构：[1]Nuffield Department of Population Health, The George Institute for Global Health, University of Oxford, Oxford, UK[2]The George Institute for Global Health, University of Sydney, Sydney, Australia[3]Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA[4]Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands[5]Department of Epidemiology and Public Health, University College London, London, UK[6]Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK[7]Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK[8]Department of Health Science, Shiga University of Medical Science, Shiga, Japan[9]Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China[10]Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Australia[11]Division of Epidemiology, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China[12]Faculty of Medicine and Biomedical Sciences, School of Population Health, University of Queensland, Australia[13]Xuanwu Hospital, Capital Medical University, Bejing, China首都医科大学宣武医院[14]School of Public Health, The University of Hong Kong, Hong Kong, China[15]Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Thailand
Objectives: In Western countries, lower socioeconomic status is associated with a higher risk of cardiovascular disease (CVD) and premature mortality. These associations may plausibly differ in Asian populations, but data are scarce and direct comparisons between the two regions are lacking. We, thus, aimed to compare such associations between Asian and Western populations in a large collaborative study, using the highest level of education attained as our measure of social status. Setting: Cohort studies in general populations conducted in Asia or Australasia. Participants: 303 036 people (71% from Asia) from 24 studies in the Asia Pacific Cohort Studies Collaboration. Studies had to have a prospective cohort study design, have accumulated at least 5000 person-years of follow-up, recorded date of birth (or age), sex and blood pressure at baseline and date of, or age at, death during follow-up. Outcome measures: We used Cox regression models to estimate relationships between educational attainment and CVD (fatal or non-fatal), as well as all-cause, cardiovascular and cancer mortality. Results: During more than two million person-years of follow-up, 11 065 deaths (3655 from CVD and 4313 from cancer) and 1809 CVD non-fatal events were recorded. Adjusting for classical CVD risk factors and alcohol drinking, hazard ratios (95% CIs) for primary relative to tertiary education in Asia (Australasia) were 1.81 (1.38, 2.36) (1.10 (0.99, 1.22)) for all-cause mortality, 2.47(1.47, 4.17) (1.24 (1.02, 1.51)) for CVD mortality, 1.66 (1.00, 2.78) (1.01 (0.87, 1.17)) for cancer mortality and 2.09 (1.34, 3.26) (1.23 (1.04, 1.46)) for all CVD. Conclusions: Lower educational attainment is associated with a higher risk of CVD or premature mortality in Asia, to a degree exceeding that in the Western populations of Australasia.
第一作者机构：[1]Nuffield Department of Population Health, The George Institute for Global Health, University of Oxford, Oxford, UK[2]The George Institute for Global Health, University of Sydney, Sydney, Australia[3]Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA
通讯作者：
通讯机构：[1]Nuffield Department of Population Health, The George Institute for Global Health, University of Oxford, Oxford, UK[2]The George Institute for Global Health, University of Sydney, Sydney, Australia[3]Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA
推荐引用方式(GB/T 7714)：
Mark Woodward ,Sanne A E Peters ,G David Batty ,et al.Socioeconomic status in relation to cardiovascular disease and cause-specific mortality: a comparison of Asian and Australasian populations in a pooled analysis[J].BMJ OPEN.2015,5(3):e006408.doi:10.1136/bmjopen-2014-006408.
APA：
Mark Woodward,,Sanne A E Peters,,G David Batty,,Hirotsugu Ueshima,,Jean Woo,...&Prin Vathesatogkit,.(2015).Socioeconomic status in relation to cardiovascular disease and cause-specific mortality: a comparison of Asian and Australasian populations in a pooled analysis.BMJ OPEN,5,(3)
MLA：
Mark Woodward,,et al."Socioeconomic status in relation to cardiovascular disease and cause-specific mortality: a comparison of Asian and Australasian populations in a pooled analysis".BMJ OPEN 5..3(2015):e006408
