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Frontotemporal Lobar Degeneration with Accumulation of Argyrophilic Grains and Lewy Bodies: A Clinicopathological Report

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收录情况： ◇ SCIE

作者：

机构： [a]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [b]Department of Geriatric Neurology, Chinese PLA General Hospital, Beijing, China [c]German Center for Neurodegenerative Diseases, Munich, Germany [d]Center for Neuropathology and Prion Research, Ludwig-Maximilians-University Munich, Munich, Germany [e]Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, Munich, Germany

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关键词： Argyrophilic grains frontotemporal lobar degeneration FTLD-tau Lewy bodies

摘要：

A clinicopathological investigation was conducted on a case of an 89-year-old man with a 10-year history of progressive dementia who also suffered strokes, apathy, aphasia, dysarthria, weakness of both legs, and walking difficulties. At autopsy, we found an obvious atrophy of the frontal and temporal cortex. Lewy bodies (LBs) could be seen in brain stem, amygdala, and neocortex. Argyrophilic grains were observed in hippocampus, entorhinal cortex, neocortex, amygdala, and pons, as well as neurofibrillary tangles in the entorhinal cortex and hippocampus. The case presented here is a rare case of frontotemporal lobar degeneration with accumulation of argyrophilic grains and Lewy bodies.

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出版当年[2014]版：

大类 | 2 区医学

小类 | 3 区神经科学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区神经科学

JCR分区：

出版当年[2013]版：

Q2 NEUROSCIENCES

最新[2023]版：

Q2 NEUROSCIENCES

影响因子： 3.4 最新[2023版] 4.2 最新五年平均 3.612 出版当年[2013版] 4.045 出版当年五年平均 4.174 出版前一年[2012版] 4.151 出版后一年[2014版]

第一作者：

第一作者机构： [a]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China

通讯作者：

通讯机构： [*1]Department of Geriatric Neurology, Chinese PLA General Hospital, Beijing 100853, China.

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