机构:[1]Department of Rheumatology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University,老年医学科首都医科大学宣武医院[2]Department of Geriatrics, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing, China老年医学科首都医科大学宣武医院
Aim To evaluate the prevalence and risk factors of gout and hyperuricemia in an elderly community cohort in Beijing. Method A total of 10039 individuals aged 50years or older participated in the study, based on the Beijing Longitudinal Study on Aging II (BLSA II) Cohort in 2009. All participants were asked for a Gout Assessment Questionnaire under the guidelines of the American College of Rheumatology. The prevalence of gout and hyperuricemia were evaluated. The potential risk factors for gout and hyperuricemia were analyzed by logistic regression. Results In our BLSA II cohort, the prevalence of gout and hyperuricemia were 2.8% and 18.1%, respectively. The prevalence of gout in the Han population was significantly lower than that in Hui population (2.6% vs. 5.8%). The traditional risk factors (age and body mass index [BMI] and metabolic syndrome [ms]) were significantly associated with the risk of gout and hyperuricemia (age: OR 1.2, 95%CI 1.1-1.5 for gout; OR 1.3, 95%CI 1.1-1.4 for hyperuricemia, respectively; BMI: OR 1.6, 95%CI 1.3-2.0; OR 1.5, 95%CI 1.3-1.8; ms: OR 2.6, 95%CI 2.0-3.3; OR 2.0, 95%CI 1.7-2.2). Family history was strongly associated with an increased risk of gout (OR 6.5, 95%CI 3.9-10.8). Conclusion Our study showed that the prevalence of both gout and hyperuricemia in Beijing remains substantial. The prevalence in the Hui population was higher than other ethnic groups. The traditional risk factors were strong risk factors for gout and hyperuricemia in China.
基金:
the Commission of Science and Technology of Beijing (D07050701130000),
Ministry of Science and Technology of China (2012AA02A514),
the Beijing High Standard Health Human Resource Cultural Program in Health System (2009e1e12).
第一作者机构:[1]Department of Rheumatology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University,[2]Department of Geriatrics, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing, China
通讯作者:
通讯机构:[*1]Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, #45 Changchun Street, Beijing 100053, China.
推荐引用方式(GB/T 7714):
Xiaolan LU ,Xiaoxia LI ,Yi ZHAO ,et al.Contemporary epidemiology of gout and hyperuricemia in community elderly in Beijing[J].INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES.2014,17(4):400-407.doi:10.1111/1756-185X.12156.
APA:
Xiaolan LU,,Xiaoxia LI,,Yi ZHAO,,Zheng ZHENG,,Shaochen GUAN&Piu CHAN.(2014).Contemporary epidemiology of gout and hyperuricemia in community elderly in Beijing.INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES,17,(4)
MLA:
Xiaolan LU,,et al."Contemporary epidemiology of gout and hyperuricemia in community elderly in Beijing".INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES 17..4(2014):400-407