机构:[1]School of Medical Information Engineering, Jining Medical University, Jining 272067, China[2]State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China[3]Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing 100875, China[4]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China神经外科首都医科大学宣武医院[5]Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China
Epilepsy is a disease of abnormal neural activities involving large area of brain networks. Until now the nature of functional brain network associated with epilepsy is still unclear. Recent researches indicate that the small world or scale-free attributes and the occurrence of highly clustered connection patterns could represent a general organizational principle in the human brain functional network. In this paper, we seek to find whether the small world or scale-free property of brain network is correlated with epilepsy seizure formation. A mass neural model was adopted to generate multiple channel EEG recordings based on regular, small world, random, and scale-free network models. Whether the connection patterns of cortical networks are directly associated with the epileptic seizures was investigated. The results showed that small world and scale-free cortical networks are highly correlated with the occurrence of epileptic seizures. In particular, the property of small world network is more significant during the epileptic seizures.
基金:
the National Science Foundation of China (nos. 61273063 and 81230023)
第一作者机构:[1]School of Medical Information Engineering, Jining Medical University, Jining 272067, China
通讯作者:
通讯机构:[5]Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China
推荐引用方式(GB/T 7714):
Yan Ni,YinghuaWang,Tao Yu,et al.Analysis of Epileptic Seizures with Complex Network[J].COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE.2014,2014:doi:10.1155/2014/283146.
APA:
Yan Ni,YinghuaWang,Tao Yu&Xiaoli Li.(2014).Analysis of Epileptic Seizures with Complex Network.COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE,2014,
MLA:
Yan Ni,et al."Analysis of Epileptic Seizures with Complex Network".COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE 2014.(2014)