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Curative effect of warming kidney and fortifying spleen recipe on diarrhea-predominant irritable bowel syndrome

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机构: [1]Department of Gastroenterology, Wangjing Hospital of China Academy of Traditional Chinese Medicine, Beijing 100102, China [2]Department of Gastroenterology, Tianjin Nankai Hospital, Tianjin 300100, China [3]Department of Gastroenterology, Xuanwu Hospital of Traditional Chinese Medicine, Beijing 100050, China [4]Department of Gastroenterology, Shanghai Seventh People's Hospital, Shanghai 200137, China
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关键词: Irritable bowel syndrome Medicine Chinese traditional Warming kidney and fortifying spleen

摘要:
OBJECTIVE: To observe the curative effect of a recipe for warming the kidney and fortifying the spleen on diarrhea-predominant irritable bowel syndrome (IBS-D). METHODS: This multi-center, double-blind, randomized, and controlled trial included 240 patients that met the inclusion criterion and were then divided into two groups of 120. Patients in the treatment group (group A) took modified Sishen Wan orally for warming the kidney and fortifying the spleen and patients in the control group (group B) took a placebo, Chao Maiya, for 4 weeks. 28 days after withdrawal, there was a 6-month follow-up to observe patient recurrence condition. The total effective rate, curative effect, and recurrence rate were evaluated after treatment. RESULTS: There was statistical difference (P<0.01) between the two groups in total effective rate (92.24% in the treatment group and 49.07% in the control group), in curative effect of TCM syndrome (90.52% and 47.22%, respectively), and in the recurrence rate (15.79% and 56.86%, respectively) within 6 months after treatment. CONCLUSION: Modified Sishen Wan, for warming the kidney and fortifying the spleen, can effectively treat IBS-D and better control its recurrence. (C) 2013 JTCM. All rights reserved.

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出版当年[2012]版:
大类 | 4 区 医学
小类 | 4 区 全科医学与补充医学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 全科医学与补充医学
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出版当年[2011]版:
Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE
最新[2023]版:
Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

影响因子: 最新[2023版] 最新五年平均 出版当年[2011版] 出版当年五年平均 出版前一年[2010版] 出版后一年[2012版]

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第一作者机构: [1]Department of Gastroenterology, Wangjing Hospital of China Academy of Traditional Chinese Medicine, Beijing 100102, China
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通讯机构: [*1]Department of Gastroenterology, Wangjing Hospital, Beijing 100102, China.
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