机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.神经内科首都医科大学宣武医院[2]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China神经内科首都医科大学宣武医院[1]Department of Neurology Xuanwu Hospital, Capital Medical University Beijing 100053, China神经内科首都医科大学宣武医院
PURPOSE: To evaluate hemodynamic effects of mannitol infusion in patients with acute intracerebral hemorrhage. METHODS: Thirty patients with acute intracerebral hemorrhage were enrolled. Transcranial doppler was used to detect variables of bilateral middle cerebral arteria (MCA) including mean velocity (Vm) and pulsitility index (PI) before and after125ml and 250ml mannitol infusion (0, 30, 60, 90, 120, 180, 240 min). RESULTS: When 125ml or 250ml mannitol was infused in patients with acute intracerebral hemorrhage, Vm of bilateral MCA elevated, and reached the top at 30min, and then decreased. PI decreased in the affected MCA (250ml) and in the unaffected MCA (125ml and 250ml). CONCLUSION: Mannitol infusion in patients with acute intracerebral hemorrhage can improve cerebral blood flow in bilateral hemispheres and decrease intracranial pressure in the hemorrhagic hemisphere (250ml) and in the nonhemorrhagic hemisphere (125ml and 250ml).
第一作者机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.[1]Department of Neurology Xuanwu Hospital, Capital Medical University Beijing 100053, China
通讯作者：
推荐引用方式(GB/T 7714)：
Hong Ye,Yingying Su.Hemodynamic effects of mannitol infusion in patients with acute intracerebral hemorrhage[J].ACTA CIRURGICA BRASILEIRA.2013,28(2):106-111.doi:10.1590/S0102-86502013000200004.
APA：
Hong Ye&Yingying Su.(2013).Hemodynamic effects of mannitol infusion in patients with acute intracerebral hemorrhage.ACTA CIRURGICA BRASILEIRA,28,(2)
MLA：
Hong Ye,et al."Hemodynamic effects of mannitol infusion in patients with acute intracerebral hemorrhage".ACTA CIRURGICA BRASILEIRA 28..2(2013):106-111
