机构:[1]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China,放射科首都医科大学宣武医院[2]State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China,[3]Department of Radiology and Biomedical Research Imaging Center, The University of North Carolina at Chapel Hill (UNC-CH), Chapel Hill, North Carolina
Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
基金:
Ministry of Science and Technology of China [2006AA02z391, 2005CB522800, 2004CB318101]; National Natural Science Foundation of China [30621004]; Knowledge Innovation Program of the Chinese Academy of Sciences
第一作者机构:[1]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China,
共同第一作者:
通讯作者:
通讯机构:[1]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China,[2]State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China,
推荐引用方式(GB/T 7714):
Wang Xing,Chen Nan,Zuo ZhenTao,et al.Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects[J].PLOS ONE.2013,8(1):e50939.doi:10.1371/journal.pone.0050939.
APA:
Wang Xing,Chen Nan,Zuo ZhenTao,Xue Rong,Jing Luo...&Li KunCheng.(2013).Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects.PLOS ONE,8,(1)
MLA:
Wang Xing,et al."Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects".PLOS ONE 8..1(2013):e50939