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A New Self-Convertible Inferior Vena Cava Filter: Experimental In-vitro and In-vivo Evaluation

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收录情况: ◇ SCIE

机构: [1]Department of Vascular Surgery,XuanWu Hospital, Capital Medical University, Changchun Street 45#, Beijing 100053 [2]School of Materials Science & Engineering,Beijing Institute of Technology, Beijing, People’s Republic of China.
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Purpose: To evaluate using in-vitro and in-vivo models the feasibility and capture efficiency of a new self-convertible inferior vena cava filter (SCF), equipped with a biodegradable self-converting switch. Materials and Methods: Capture rates were tested in an in-vitro flow model for simulated supine and upright positions with clot diameters of 3 mm and 5 mm and tube diameters of 22 mm, 25 mm, and 28 mm. In the in-vivo study, five filters were implanted in five adult dogs. Venography was performed after the procedure every 2 weeks until filter conversion. Results: All filters were successfully implanted and completely converted with a mean trapping efficiency of 75.5% in the in-vivo study. The SCF was most efficient at 92% in the upright orientation with 5-mm clots and a 22-mm caval diameter. All five filters exhibited successful delivery and conversion in vitro. The SCFs were manually manufactured without barbs or hooks, and because of this feature, migration occurred. Conclusions: The SCF is feasible and highly efficient and converts itself successfully. Evaluation is planned of future prototypes with appropriate modifications for risk of migration of the filter.

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基金编号: 30972944 30840077

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出版当年[2010]版:
大类 | 4 区 医学
小类 | 3 区 核医学 4 区 外周血管病
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 外周血管病 3 区 核医学
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出版当年[2009]版:
Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Q3 PERIPHERAL VASCULAR DISEASE
最新[2023]版:
Q2 PERIPHERAL VASCULAR DISEASE Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2023版] 最新五年平均 出版当年[2009版] 出版当年五年平均 出版前一年[2008版] 出版后一年[2010版]

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第一作者机构: [1]Department of Vascular Surgery,XuanWu Hospital, Capital Medical University, Changchun Street 45#, Beijing 100053
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通讯机构: [1]Department of Vascular Surgery,XuanWu Hospital, Capital Medical University, Changchun Street 45#, Beijing 100053
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