机构：[a]Department of Neurosurgery, Xuanwu Hospital, The Capital Medical University, Chuangchu Street 45, Beijing 100053, China神经外科首都医科大学宣武医院[b]Department of Neurology, China Rehabilitation Research Center, Fengtai District, North Road 10, Box 2619, Beijing 100077, China
Objectives: The aim of this study was to evaluate visual outcome in patients with tuberculum sellae meningioma (TSM) treated microsurgically using the frontolateral or fronto-orbital approach and optic canal unroofing to resect tumor involvement of the optic canal. Methods: Data from 67 patients with TSMs who underwent microsurgical treatment by a frontolateral approach (n = 44) or fronto-orbital approach (n = 23) between January 2002 and December 2008 were retrospectively collected and analyzed. Change in visual function was evaluated as the main outcome. Results: Total tumor resection was achieved in 62 of 67 cases (92.4%). Postoperative, visual acuity was improved in 87 eyes (64.9%) and unchanged in 39 eyes (29.1%), and the optic nerve was therefore preserved in 126 of 134 eyes (94.0%). Visual field deficits were improved or stable in 65 eyes, no patient experienced worsening of vision in both eyes. There was no mortality in our series. Conclusions: The frontolateral approach with microsurgical dissection of the Sylvian fissure provides quick access to TSMs, which can be resected safely and totally. Visual function is improved and neurological and ophthalmological morbidity is minimal. Optic nerve decompression by intradural clinoidectomy and optic canal unroofing is likely to increase the rate of reducing or eliminating preoperative visual symptoms. (C) 2010 Elsevier B.V. All rights reserved.
第一作者机构：[a]Department of Neurosurgery, Xuanwu Hospital, The Capital Medical University, Chuangchu Street 45, Beijing 100053, China
通讯作者：
通讯机构：[a]Department of Neurosurgery, Xuanwu Hospital, The Capital Medical University, Chuangchu Street 45, Beijing 100053, China
推荐引用方式(GB/T 7714)：
Chen Li-Hua,Chen Ling,Liu Li-Xu.Microsurgical management of tuberculum sellae meningiomas by the frontolateral approach: Surgical technique and visual outcome[J].CLINICAL NEUROLOGY AND NEUROSURGERY.2011,113(1):39-47.doi:10.1016/j.clineuro.2010.08.019.
APA：
Chen Li-Hua,Chen Ling&Liu Li-Xu.(2011).Microsurgical management of tuberculum sellae meningiomas by the frontolateral approach: Surgical technique and visual outcome.CLINICAL NEUROLOGY AND NEUROSURGERY,113,(1)
MLA：
Chen Li-Hua,et al."Microsurgical management of tuberculum sellae meningiomas by the frontolateral approach: Surgical technique and visual outcome".CLINICAL NEUROLOGY AND NEUROSURGERY 113..1(2011):39-47
