机构：[1]School of Biological Science and Medical Engineering, Beijing University of Aeronautics and Astronautics, Beijing, 100191 China,[2]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053 China,神经内科首都医科大学宣武医院[3]State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China,[4]Department of Radiology, Huaxi MR Research Center, West China Hospital of Sichuan University, Chengdu, 610041 China[5]Department of Radiology, First Affiliated Hospital of College of Medical Science, Zhejiang University, Hangzhou, 310003 China
We employed a sulcal geometry-based approach to investigate the morphology of the central sulcus (CS) in musicians (pianists). The anterior and posterior walls of the CS were first manually outlined from high-resolution magnetic resonance (MR) images of 41 right-handed subjects (20 musicians and 21 controls), followed by a surface reconstruction and parameterization procedure to ensure the anatomical correspondence of surface locations across subjects. The intrasulcal length, surface area, and local variability of the CS were measured. There were no significant differences in either the intrasulcal length or surface area of the anterior or posterior walls between the 2 groups. However, we observed that the controls had a pronounced left-larger-than-right asymmetry that was reduced in the musicians. Importantly, we found that the musicians showed greater local variability in the middle section (i.e., somatotopic hand area) of the right CS and the lower section of the left CS as compared with the controls. Further analysis revealed significantly negative correlations between the variability of the middle section of the right CS and the age of commencement of musical training. Our findings suggest that the musicians might be associated with plastic changes in the 3D morphology of the CS in response to long-term motor skill training.
基金：
Natural Science Foundation of China (grant nos. 30700182, 30870667, 30470575, 30625024, 30530290, and 30621130074); the Scientific Research Foundation for the Returned Overseas Chinese Scholars (State Education Ministry);
the National Basic Research Program (973 program no.: 2007CB512305); National High Technology Program of China (863 program no.: 2008AA02Z408).
第一作者机构：[1]School of Biological Science and Medical Engineering, Beijing University of Aeronautics and Astronautics, Beijing, 100191 China,
共同第一作者：
通讯作者：
通讯机构：[3]State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China,
推荐引用方式(GB/T 7714)：
Shuyu Li,Ying Han,Deyi Wang,et al.Mapping Surface Variability of the Central Sulcus in Musicians[J].CEREBRAL CORTEX.2010,20(1):25-33.doi:10.1093/cercor/bhp074.
APA：
Shuyu Li,Ying Han,Deyi Wang,Hong Yang,Yubo Fan...&Yong He.(2010).Mapping Surface Variability of the Central Sulcus in Musicians.CEREBRAL CORTEX,20,(1)
MLA：
Shuyu Li,et al."Mapping Surface Variability of the Central Sulcus in Musicians".CEREBRAL CORTEX 20..1(2010):25-33
