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Decreased gyrification in major depressive disorder

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收录情况： ◇ SCIE

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机构： [a]Department of Mathematics, Zhejiang University, Hangzhou, [b]National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, [c]Department of Radiology, Xuanwu Hospital of Capital Medical University [d]Center for Social and Economic Behavior, Institute of Psychology, Chinese Academy of Sciences, Beijing, PR China

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关键词： complexity connectivity cortical folding local gyrification index magnetic resonance imaging major depressive disorder

摘要：

Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive disorder and 18 age-matched and sex-matched healthy individuals. The local gyrification index was applied to detect brain areas with abnormal cortical folding in major depressive disorder. Compared with healthy participants, patients with major depressive disorder showed significantly decreased local gyrification index in the bilateral mid-posterior cingulate, insula, and orbital frontal cortices, the left anterior cingulate cortex, and the right temporal operculum. NeuroReport 20:378-380 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.

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出版当年[2008]版：

大类 | 3 区医学

小类 | 4 区神经科学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区神经科学

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出版当年[2007]版：

Q3 NEUROSCIENCES

最新[2023]版：

Q4 NEUROSCIENCES

影响因子： 1.6 最新[2023版] 1.6 最新五年平均 2.163 出版当年[2007版] 2.484 出版当年五年平均 2.137 出版前一年[2006版] 1.904 出版后一年[2008版]

第一作者：

第一作者机构： [a]Department of Mathematics, Zhejiang University, Hangzhou, [b]National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences,

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通讯作者：

通讯机构： [*]National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, PR China

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