机构：[a]Carestream Health Global R&D (Shanghai), Building 4, Jinqiao Software Park, No.27, Xin Jinqiao Road, Pudong, Shanghai, China[b]Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing, China放射科首都医科大学宣武医院[c]Department of Radiology, Renji Hospital of Shanghai Jiaotong University, Shanghai, China[d]School of Life Sciences and Biotechnology, Shanghai Jiaotong University, Shanghai, China
This study is to investigate the incremental effect of using a high performance computer-aided detection (CAD) system in detection of solitary pulmonary nodules in chest radiographs. The Kodak Chest CAD system was evaluated by a panel of six radiologists at different levels of experience. The observer study consisted of two independent phases: readings without CAD and readings with assistance of CAD. The study was conducted over a set of chest radiographs comprising 150 cancer cases and 150 cancer-free cases. The actual sensitivity of the CAD system is 72% with 3.7 false positives per case. Receiver operating characteristic (ROC) analysis was used to assess the overall observer performance. The AUZ (area under ROC curve) showed a significantly improvement (P=0.0001) from 0.844 to 0.884 after using CAD. The ROC analysis was also applied for observer performances on nodules in different sizes and visibilities. The average AUZs are improved from 0.798 to 0.835 (P=0.0003) for 5-10mm nodules, 0.853 to 0.907 (P=0.001) for 10-15mm nodules, 0.864 to 0.897 (P=0.051) for 15-20 mm nodules and 0.859 to 0.896 (P=0.0342) for 20-30mm nodules, respectively. For different visibilities, the average AUZs are improved from 0.886 to 0.915 (P=0.0337), 0.803 to 0.840 (P=0.063), 0.830 to 0.893 (P=0.0001), and 0.813 to 0.847 (P=0.152), for nodules clearly visible, hidden by ribs, partially overlap with ribs, and overlap with other structures, respectively. These results showed that observer performance could be greatly improved when the CAD system is employed as a second reader, especially for small nodules and nodules occluded by ribs.
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第一作者机构：[a]Carestream Health Global R&D (Shanghai), Building 4, Jinqiao Software Park, No.27, Xin Jinqiao Road, Pudong, Shanghai, China
推荐引用方式(GB/T 7714)：
Jiayong Yan,Wenjie Li,Xiangying Du,et al.Effectiveness of computer aided detection for solitary pulmonary nodules[J].MEDICAL IMAGING 2009: IMAGE PERCEPTION, OBSERVER PERFORMANCE, AND TECHNOLOGY ASSESSMENT.2009,7263:doi:10.1117/12.804716.
APA：
Jiayong Yan,Wenjie Li,Xiangying Du,Huihai Lu,Jianrong Xu...&Dongdong Rong.(2009).Effectiveness of computer aided detection for solitary pulmonary nodules.MEDICAL IMAGING 2009: IMAGE PERCEPTION, OBSERVER PERFORMANCE, AND TECHNOLOGY ASSESSMENT,7263,
MLA：
Jiayong Yan,et al."Effectiveness of computer aided detection for solitary pulmonary nodules".MEDICAL IMAGING 2009: IMAGE PERCEPTION, OBSERVER PERFORMANCE, AND TECHNOLOGY ASSESSMENT 7263.(2009)
