机构：[a]Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Road, Beijing 100049, China[b]General Hospital of Chinese People’s Armed Police Forces, Beijing, China[c]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing, China放射科首都医科大学宣武医院[d]Xuzhou Medical College, Xuzhou, China[e]Department of Physics, Zhejiang University, Hangzhou, China
Specific central nervous system (CNS) responses to acupuncture have recently attracted attention. It is important to understand the differences in fMRI images of the brain evoked by acupuncture at an acupoint and at a nearby "sham" point. Here, we report analyses of fMRI images of the brains of 37 healthy volunteers in response to acupuncture at Liv3 (Taichong) and LI4 (Hegu) versus their sham points. We found common activation areas in response to Liv3 or LI4 acupuncture in the middle temporal gyrus and cerebellum, along with deactivation areas in the middle frontal gyrus and inferior parietal lobule, compared with the effects of acupuncture at sham points. Acupuncture at Liv3 evoked specific activation at the postcentral gyrus, posterior cingulate, parahippocampal gyrus, BA 7, 19 and 4 1, but deactivation at the inferior frontal gyrus, anterior cingulate, BA 17 and 18, compared with acupuncture at its sham point. Acupuncture at LI4 evoked specific activation at the temporal pole, but deactivation at the precentral gyrus, superior temporal gyrus, pulvinar and BA 8, 9 and 45, compared with acupuncture at its sham point. These observations reveal that acupuncture at acupoints induces specific patterns of brain activity, and these patterns may relate to the therapeutic effects of acupuncture. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
基金：
National Natural Science Foundation of China (Grant Number 90209030).
第一作者机构：[a]Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Road, Beijing 100049, China
通讯作者：
通讯机构：[a]Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, 19 Yu Quan Road, Beijing 100049, China
推荐引用方式(GB/T 7714)：
Bin Yan,Ke Li,Jianyang Xu,et al.Acupoint-specific fMRI patterns in human brain[J].NEUROSCIENCE LETTERS.2005,383(3):236-240.doi:10.1016/j.neulet.2005.04.021.
APA：
Bin Yan,Ke Li,Jianyang Xu,Wei Wang,Kuncheng Li...&Xiaowei Tang.(2005).Acupoint-specific fMRI patterns in human brain.NEUROSCIENCE LETTERS,383,(3)
MLA：
Bin Yan,et al."Acupoint-specific fMRI patterns in human brain".NEUROSCIENCE LETTERS 383..3(2005):236-240
