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Detection of a human parvovirus intrauterine infection with the polymerase chain reaction

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机构: [1]Natl Res Inst Family Planning, Dept Mol Biol, Beijing 100081, Peoples R China [2]Beijing Xuanwu Hosp, Dept Obstet & Gynecol, Beijing, Peoples R China [3]Natl Res Inst Family Planning, Dept Mol Biol, 12 Da Hui Si, Beijing 100081, Peoples R China
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关键词: parvovirus B19 human polymerase chain reaction chorionic villi sampling

摘要:
OBJECTIVE: To detect human parvovirus B19 intrauterine infection in pregnancy with the polymerase chain reaction (PCR). STUDY DESIGN: DNA of chorionic villi and amniotic fluid was extracted and the gene of human parvovirus B19 amplified with PCR. RESULTS: The study analyzed 61 specimens of chorionic villi and 26 specimens of amniotic fluid and found two positive specimens of chorionic villi and I positive specimen of amniotic fluid. CONCLUSION: The vertical transmission of human parvovirus B19 infection in early pregnancy may be a pathway of intrauterine infection. Chorionic villus sampling in early pregnancy and PCR could be developed as a method of prenatal diagnosis of human parvovirus B19 intrauterine infection.

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出版当年[1999]版:
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学
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出版当年[1998]版:
Q3 OBSTETRICS & GYNECOLOGY
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影响因子: 最新[2023版] 最新五年平均 出版当年[1998版] 出版当年五年平均 出版前一年[1997版] 出版后一年[1999版]

第一作者:
第一作者机构: [1]Natl Res Inst Family Planning, Dept Mol Biol, Beijing 100081, Peoples R China [2]Beijing Xuanwu Hosp, Dept Obstet & Gynecol, Beijing, Peoples R China [3]Natl Res Inst Family Planning, Dept Mol Biol, 12 Da Hui Si, Beijing 100081, Peoples R China
通讯作者:
通讯机构: [3]Natl Res Inst Family Planning, Dept Mol Biol, 12 Da Hui Si, Beijing 100081, Peoples R China
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