机构：[a]Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing, 100700, China[b]Beijing Geriatric Clinic and Research Center, Beijing Xuanwu Hospital, Beijing, 100053, China首都医科大学宣武医院北京市老年病医疗研究中心
出处：
ISSN：
摘要：
Shear-induced platelet aggregation (SIPA) plays an important role in vascular diseases. In this study, SIPA was generated by a computerized cone-plate apparatus. Six compounds from Chinese herbal medicine were selected for in vitro and in vivo tests. Rabbit and rat were involved in the tests accordingly. Ligustrazine hydrochloridi appeared to be most effective for inhibition of SIPA. The inhibition rate of SIPA reached 44.2% (p < 0.01) for an in vitro concentration of 1 mg/ml, and 46.1% (p < 0.01) for an in vivo dose of 50 mg/kg.
第一作者机构：[*]Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, No. 18, Beixincang, East District, Beijing, 100700, China.
通讯作者：
通讯机构：[*]Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, No. 18, Beixincang, East District, Beijing, 100700, China.
推荐引用方式(GB/T 7714)：
Fu-long Liaoa,Bin Li.Inhibition of shear-induced platelet aggregation by Chinese herbal medicines[J].CLINICAL HEMORHEOLOGY AND MICROCIRCULATION.1997,17(4):315-318.
APA：
Fu-long Liaoa&Bin Li.(1997).Inhibition of shear-induced platelet aggregation by Chinese herbal medicines.CLINICAL HEMORHEOLOGY AND MICROCIRCULATION,17,(4)
MLA：
Fu-long Liaoa,et al."Inhibition of shear-induced platelet aggregation by Chinese herbal medicines".CLINICAL HEMORHEOLOGY AND MICROCIRCULATION 17..4(1997):315-318
